Loryna and Mood swings - a phase IV clinical study of FDA data

Summary:

Mood swings is reported as a side effect among people who take Loryna (drospirenone; ethinyl estradiol), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Vitamin D3, and have Acne.

The phase IV clinical study analyzes which people have Mood swings when taking Loryna. It is created by eHealthMe based on reports of 336 people who have side effects when taking Loryna from the FDA, and is updated regularly.

What is Loryna?

Loryna has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 388 Loryna users. Check the latest studies of Loryna.

What is Mood swings?

Mood swings (an extreme or rapid change in mood) is found to be associated with 1,679 drugs and 2,129 conditions by eHealthMe. Check the latest studies of Mood swings.

On Jul, 20, 2026

336 people reported to have side effects when taking Loryna.
Among them, 14 people (4.17%) have Mood swings.

Among these 14 people:

How long have people been on Loryna when they have Mood swings? *

What is the gender of people who have Mood swings when taking Loryna? *

female: 100 %
male: 0.0 %

What is the age of people who have Mood swings when taking Loryna? *

What are other drugs people take besides Loryna? *

What are other side effects people have besides Mood swings? *

Depression: 6 people, 42.86%
Fatigue (feeling of tiredness): 5 people, 35.71%
Irritability: 4 people, 28.57%
Nausea (feeling of having an urge to vomit): 3 people, 21.43%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 21.43%
Headache (pain in head): 3 people, 21.43%
Crying: 3 people, 21.43%
Dizziness: 3 people, 21.43%
Depressed Mood: 2 people, 14.29%
Joint Pain: 2 people, 14.29%

What are the existing conditions these people have? *

Acne (skin problems that cause pimples): 4 people, 28.57%
Depression: 3 people, 21.43%
Pain: 2 people, 14.29%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 7.14%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 1 person, 7.14%
Migraine (headache): 1 person, 7.14%
Drowsiness: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Loryna and have Mood swings?

- Check whether Mood swings is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Loryna:

Loryna (388 reports)

Mood swings treatments and more:

Mood swings (74,716 reports)

How severe was Mood swings and when was it recovered:

Mood swings in Loryna

Expand to all the drugs that have ingredients of drospirenone; ethinyl estradiol:

Mood swings and drugs with ingredients of drospirenone; ethinyl estradiol (458 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loryna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mood swings:

Mood swings (1,679 drugs)

Browse all the conditions that are associated with Mood swings:

Mood swings (2,129 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on drospirenone; ethinyl estradiol (the active ingredients of Loryna) and Loryna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.