Losartan and Distributive shock - a phase IV clinical study of FDA data

Summary:

Distributive shock is reported as a side effect among people who take Losartan (losartan potassium), especially for people who are male, 50-59 old, also take Amlodipine, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Distributive shock when taking Losartan. It is created by eHealthMe based on reports of 170,768 people who have side effects when taking Losartan from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,692 Losartan users. Check the latest studies of Losartan.

What is Distributive shock?

Distributive shock (hock caused by poor distribution of the blood flow) is found to be associated with 117 drugs and 123 conditions by eHealthMe. Check the latest studies of Distributive shock.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

170,768 people reported to have side effects when taking Losartan.
Among them, 12 people (0.01%) have Distributive shock.

Could Losartan cause Distributive shock?

Among these 12 people:

What is the gender of people who have Distributive shock when taking Losartan? *

female: 45.45 %
male: 54.55 %

What is the age of people who have Distributive shock when taking Losartan? *

What are other drugs people take besides Losartan? *

Amlodipine: 11 people, 91.67%
Metformin: 5 people, 41.67%
Metformin Hydrochloride: 3 people, 25.00%
Aripiprazole: 3 people, 25.00%
Valacyclovir: 1 person, 8.33%
Solu-Medrol: 1 person, 8.33%
Pantoprazole: 1 person, 8.33%
Ondansetron: 1 person, 8.33%

What are other side effects people have besides Distributive shock? *

Lactic Acidosis (low ph in body tissues): 9 people, 75.00%
Cardiogenic Shock (inadequate circulation of blood): 6 people, 50.00%
Overdose: 3 people, 25.00%
Hypotension (abnormally low blood pressure): 3 people, 25.00%
Systemic Inflammatory Response Syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection): 1 person, 8.33%
Hepatic Enzyme Increased: 1 person, 8.33%
Acidosis (build-up of carbon dioxide in the blood): 1 person, 8.33%
Acute Myocardial Infarction (acute heart attack): 1 person, 8.33%
Atelectasis (partial or complete collapse of the lung): 1 person, 8.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%

What are the existing conditions these people have? *

Type 2 Diabetes: 5 people, 41.67%
Nausea And Vomiting: 1 person, 8.33%
Nausea (feeling of having an urge to vomit): 1 person, 8.33%
Insomnia (sleeplessness): 1 person, 8.33%
Indigestion: 1 person, 8.33%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 8.33%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and have Distributive shock?

- Check whether Distributive shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Losartan:

Losartan (177,692 reports)

Browse all side effects of Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Distributive shock:

Distributive shock (117 drugs)

Browse all the conditions that are associated with Distributive shock:

Distributive shock (123 conditions)

Related publications that referenced our studies

Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium (the active ingredients of Losartan) and Losartan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.