Losartan and Enthesopathy - a phase IV clinical study of FDA data

Summary:

Enthesopathy is reported as a side effect among people who take Losartan (losartan potassium), especially for people who are female, 50-59 old, also take Humira, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Enthesopathy when taking Losartan. It is created by eHealthMe based on reports of 170,768 people who have side effects when taking Losartan from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,692 Losartan users. Check the latest studies of Losartan.

What is Enthesopathy?

Enthesopathy (disorder of entheses (bone attachments)) is found to be associated with 274 drugs and 204 conditions by eHealthMe. Check the latest studies of Enthesopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

170,768 people reported to have side effects when taking Losartan.
Among them, 80 people (0.05%) have Enthesopathy.

Among these 80 people:

What is the gender of people who have Enthesopathy when taking Losartan? *

female: 98.63 %
male: 1.37 %

What is the age of people who have Enthesopathy when taking Losartan? *

What are other drugs people take besides Losartan? *

What are other side effects people have besides Enthesopathy? *

Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 74 people, 92.50%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 73 people, 91.25%
Drug Ineffective: 73 people, 91.25%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 73 people, 91.25%
Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon): 73 people, 91.25%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 72 people, 90.00%
Oral Pain: 69 people, 86.25%
Stomatitis (inflammation of mucous membrane of mouth): 68 people, 85.00%
Joint Pain: 4 people, 5.00%
Stress And Anxiety: 4 people, 5.00%

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 75 people, 93.75%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 3.75%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 2.50%
Hypersensitivity: 2 people, 2.50%
Headache (pain in head): 2 people, 2.50%
Urinary Tract Infection: 1 person, 1.25%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 1.25%
Spondyloarthropathy (any joint disease of the vertebral column): 1 person, 1.25%
Multiple Myeloma (cancer of the plasma cells): 1 person, 1.25%
High Blood Cholesterol: 1 person, 1.25%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and have Enthesopathy?

- Check whether Enthesopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Losartan:

Losartan (177,692 reports)

Enthesopathy treatments and more:

Enthesopathy (2,364 reports)

Browse all side effects of Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enthesopathy:

Enthesopathy (274 drugs)

Browse all the conditions that are associated with Enthesopathy:

Enthesopathy (204 conditions)

Related publications that referenced our studies

Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium (the active ingredients of Losartan) and Losartan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.