Losartan and Lower extremity mass - a phase IV clinical study of FDA data

Summary:

Lower extremity mass is reported as a side effect among people who take Losartan (losartan potassium), especially for people who are female, 40-49 old, also take Humira, and have Pain.

The phase IV clinical study analyzes which people have Lower extremity mass when taking Losartan. It is created by eHealthMe based on reports of 170,768 people who have side effects when taking Losartan from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,692 Losartan users. Check the latest studies of Losartan.

What is Lower extremity mass?

Lower extremity mass (mass in lower legs) is found to be associated with 161 drugs and 298 conditions by eHealthMe. Check the latest studies of Lower extremity mass.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

170,768 people reported to have side effects when taking Losartan.
Among them, 13 people (0.01%) have Lower extremity mass.

Could Losartan cause Lower extremity mass?

Among these 13 people:

What is the gender of people who have Lower extremity mass when taking Losartan? *

female: 92.31 %
male: 7.69 %

What is the age of people who have Lower extremity mass when taking Losartan? *

What are other drugs people take besides Losartan? *

What are other side effects people have besides Lower extremity mass? *

Malaise (a feeling of general discomfort or uneasiness): 7 people, 53.85%
Vision Blurred: 6 people, 46.15%
Fever: 6 people, 46.15%
Joint Pain: 6 people, 46.15%
Drowsiness: 6 people, 46.15%
Dizziness: 6 people, 46.15%
Wound: 5 people, 38.46%
Pain In Extremity: 5 people, 38.46%
Headache (pain in head): 5 people, 38.46%
Gait Disturbance: 5 people, 38.46%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 46.15%
Pain: 6 people, 46.15%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 30.77%
Immunodeficiency: 3 people, 23.08%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 15.38%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 2 people, 15.38%
Thyroid Diseases: 1 person, 7.69%
Swelling: 1 person, 7.69%
Petit Mal Epilepsy (absence seizure): 1 person, 7.69%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and have Lower extremity mass?

- Check whether Lower extremity mass is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Losartan:

Losartan (177,692 reports)

Browse all side effects of Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lower extremity mass:

Lower extremity mass (161 drugs)

Browse all the conditions that are associated with Lower extremity mass:

Lower extremity mass (298 conditions)

Related publications that referenced our studies

Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium (the active ingredients of Losartan) and Losartan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.