Losartan and Narcolepsy - a phase IV clinical study of FDA data

Summary:

Narcolepsy is reported as a side effect among people who take Losartan (losartan potassium), especially for people who are male, 50-59 old, also take Xyrem, and have Diabetes.

The phase IV clinical study analyzes which people have Narcolepsy when taking Losartan. It is created by eHealthMe based on reports of 170,768 people who have side effects when taking Losartan from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.

What is Narcolepsy?

Narcolepsy (brain's inability to regulate sleep-wake cycles normally) is found to be associated with 429 drugs and 738 conditions by eHealthMe. Check the latest studies of Narcolepsy.

On Jul, 15, 2026

170,768 people reported to have side effects when taking Losartan.
Among them, 26 people (0.02%) have Narcolepsy.

Among these 26 people:

What is the gender of people who have Narcolepsy when taking Losartan? *

female: 41.67 %
male: 58.33 %

What is the age of people who have Narcolepsy when taking Losartan? *

What are other drugs people take besides Losartan? *

What are other side effects people have besides Narcolepsy? *

Dyspnea (difficult or laboured breathing): 9 people, 34.62%
Heart Attack: 8 people, 30.77%
Itching: 8 people, 30.77%
Fatigue (feeling of tiredness): 4 people, 15.38%
Pneumonia: 4 people, 15.38%
Weight Increased: 2 people, 7.69%
Depression: 2 people, 7.69%
Stress And Anxiety: 2 people, 7.69%
Dizziness: 2 people, 7.69%
Sleep Disorder: 2 people, 7.69%

What are the existing conditions these people have? *

Diabetes: 11 people, 42.31%
Psychotic Disorder: 8 people, 30.77%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 15.38%
Drowsiness: 4 people, 15.38%
High Blood Cholesterol: 3 people, 11.54%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 11.54%
Indigestion: 2 people, 7.69%
Depression: 2 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and have Narcolepsy?

- Check whether Narcolepsy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Losartan:

Losartan (177,686 reports)

Narcolepsy treatments and more:

Narcolepsy (79,888 reports)

Browse all side effects of Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Narcolepsy:

Narcolepsy (429 drugs)

Browse all the conditions that are associated with Narcolepsy:

Narcolepsy (738 conditions)

Related publications that referenced our studies

Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
Han SH, Lee SA, "Superficial Vein Thrombosis as the Initial Manifestation of Protein S Deficiency in an Adolescent with Narcolepsy", Sleep Medicine Research, 2016 Jun .
Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
Han SH, Lee SA, "Superficial Vein Thrombosis as the Initial Manifestation of Protein S Deficiency in an Adolescent with Narcolepsy", Sleep Medicine Research, 2016 Jun .
Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium (the active ingredients of Losartan) and Losartan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.