Lotrel and Abnormal behavior - a phase IV clinical study of FDA data

Summary:

Abnormal behavior is reported as a side effect among people who take Lotrel (amlodipine besylate; benazepril hydrochloride), especially for people who are male, 50-59 old, also take Seroquel, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Abnormal behavior when taking Lotrel. It is created by eHealthMe based on reports of 13,000 people who have side effects when taking Lotrel from the FDA, and is updated regularly.

What is Lotrel?

Lotrel has active ingredients of amlodipine besylate; benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,571 Lotrel users. Check the latest studies of Lotrel.

What is Abnormal behavior?

Abnormal behavior is found to be associated with 1,358 drugs and 1,957 conditions by eHealthMe. Check the latest studies of Abnormal behavior.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

13,000 people reported to have side effects when taking Lotrel.
Among them, 24 people (0.18%) have Abnormal behavior.

Among these 24 people:

What is the gender of people who have Abnormal behavior when taking Lotrel? *

female: 43.48 %
male: 56.52 %

What is the age of people who have Abnormal behavior when taking Lotrel? *

What are other drugs people take besides Lotrel? *

What are other side effects people have besides Abnormal behavior? *

Chest Pain: 10 people, 41.67%
Overdose: 10 people, 41.67%
Urinary Tract Infection: 9 people, 37.50%
Insomnia (sleeplessness): 8 people, 33.33%
Rashes (redness): 7 people, 29.17%
Cellulitis (infection under the skin): 7 people, 29.17%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 7 people, 29.17%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 7 people, 29.17%
Liver Disorder (liver diseases): 7 people, 29.17%
Suicide Attempt: 7 people, 29.17%

What are the existing conditions these people have? *

Stress And Anxiety: 9 people, 37.50%
Insomnia (sleeplessness): 8 people, 33.33%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 7 people, 29.17%
Quit Smoking: 7 people, 29.17%
Bipolar Disorder (mood disorder): 6 people, 25.00%
Sleep Disorder: 6 people, 25.00%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 25.00%
Pain: 4 people, 16.67%
Social Phobia (fear to go in social): 3 people, 12.50%
Diabetes: 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Lotrel and have Abnormal behavior?

- Check whether Abnormal behavior is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lotrel:

Lotrel (13,571 reports)

Abnormal behavior treatments and more:

Abnormal behavior (51,307 reports)

How severe was Abnormal behavior and when was it recovered:

Abnormal behavior in Lotrel

Expand to all the drugs that have ingredients of amlodipine besylate; benazepril hydrochloride:

Abnormal behavior and drugs with ingredients of amlodipine besylate; benazepril hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lotrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abnormal behavior:

Abnormal behavior (1,358 drugs)

Browse all the conditions that are associated with Abnormal behavior:

Abnormal behavior (1,957 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; benazepril hydrochloride (the active ingredients of Lotrel) and Lotrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.