Lotrel and Dysstasia - a phase IV clinical study of FDA data

Summary:

Dysstasia is reported as a side effect among people who take Lotrel (amlodipine besylate; benazepril hydrochloride), especially for people who are female, 60+ old, also take Hydrochlorothiazide, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Dysstasia when taking Lotrel. It is created by eHealthMe based on reports of 13,000 people who have side effects when taking Lotrel from the FDA, and is updated regularly.

What is Lotrel?

Lotrel has active ingredients of amlodipine besylate; benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,571 Lotrel users. Check the latest studies of Lotrel.

What is Dysstasia?

Dysstasia (difficulty in standing) is found to be associated with 1,386 drugs and 1,369 conditions by eHealthMe. Check the latest studies of Dysstasia.

On Jul, 17, 2026

13,000 people reported to have side effects when taking Lotrel.
Among them, 24 people (0.18%) have Dysstasia.

Among these 24 people:

What is the gender of people who have Dysstasia when taking Lotrel? *

female: 73.91 %
male: 26.09 %

What is the age of people who have Dysstasia when taking Lotrel? *

What are other drugs people take besides Lotrel? *

What are other side effects people have besides Dysstasia? *

Diarrhea: 6 people, 25.00%
Haematochezia (passage of stools containing blood): 6 people, 25.00%
Gait Disturbance: 6 people, 25.00%
Hypotension (abnormally low blood pressure): 6 people, 25.00%
Weakness: 6 people, 25.00%
Fall: 5 people, 20.83%
Back Pain: 5 people, 20.83%
Limb Discomfort (discomfort in leg): 5 people, 20.83%
Mobility Decreased (ability to move is reduced): 5 people, 20.83%
Angioedema (rapid swelling of the dermis): 4 people, 16.67%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 20.83%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 4.17%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.17%
Osteoporosis (bones weak and more likely to break): 1 person, 4.17%
Hypotonia (low muscle tone): 1 person, 4.17%
Headache (pain in head): 1 person, 4.17%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.17%
Gait Disturbance: 1 person, 4.17%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 4.17%
Dyslipidaemia (abnormal amount of lipids): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Lotrel and have Dysstasia?

- Check whether Dysstasia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lotrel:

Lotrel (13,571 reports)

Dysstasia treatments and more:

Dysstasia (35,077 reports)

How severe was Dysstasia and when was it recovered:

Dysstasia in Lotrel

Expand to all the drugs that have ingredients of amlodipine besylate; benazepril hydrochloride:

Dysstasia and drugs with ingredients of amlodipine besylate; benazepril hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lotrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dysstasia:

Dysstasia (1,386 drugs)

Browse all the conditions that are associated with Dysstasia:

Dysstasia (1,369 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; benazepril hydrochloride (the active ingredients of Lotrel) and Lotrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.