Lovastatin and Cardiac valve disease - a phase IV clinical study of FDA data

Summary:

Cardiac valve disease is reported as a side effect among people who take Lovastatin (lovastatin), especially for people who are male, 60+ old, also take Lasix, and have Diabetes.

The phase IV clinical study analyzes which people have Cardiac valve disease when taking Lovastatin. It is created by eHealthMe based on reports of 31,864 people who have side effects when taking Lovastatin from the FDA, and is updated regularly.

What is Lovastatin?

Lovastatin has active ingredients of lovastatin. It is often used in high blood cholesterol. eHealthMe is studying from 33,048 Lovastatin users. Check the latest studies of Lovastatin.

What is Cardiac valve disease?

Cardiac valve disease (heart valve disease) is found to be associated with 670 drugs and 764 conditions by eHealthMe. Check the latest studies of Cardiac valve disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

31,864 people reported to have side effects when taking Lovastatin.
Among them, 45 people (0.14%) have Cardiac valve disease.

Could Lovastatin cause Cardiac valve disease?

Among these 45 people:

What is the gender of people who have Cardiac valve disease when taking Lovastatin? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Cardiac valve disease when taking Lovastatin? *

What are other drugs people take besides Lovastatin? *

What are other side effects people have besides Cardiac valve disease? *

Dyspnea (difficult or laboured breathing): 13 people, 28.89%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 11 people, 24.44%
Stress And Anxiety: 11 people, 24.44%
Heart Attack: 9 people, 20.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 9 people, 20.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 17.78%
Weakness: 8 people, 17.78%
Diarrhea: 8 people, 17.78%
Cardiac Failure Congestive: 8 people, 17.78%
Hypotension (abnormally low blood pressure): 8 people, 17.78%

What are the existing conditions these people have? *

Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 6 people, 13.33%
Diabetes: 6 people, 13.33%
Hyperkalemia (damage to or disease of the kidney): 5 people, 11.11%
Arrhythmias (irregular heartbeat): 4 people, 8.89%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 4.44%
Urinary Tract Disorder: 2 people, 4.44%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 4.44%
Dry Eyes (lack of adequate tears): 2 people, 4.44%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 4.44%
Sensitivity Of Teeth: 1 person, 2.22%

* Approximation only. Some reports may have incomplete information.

Do you take Lovastatin and have Cardiac valve disease?

- Check whether Cardiac valve disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lovastatin:

Lovastatin (33,048 reports)

Browse all side effects of Lovastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac valve disease:

Cardiac valve disease (670 drugs)

Browse all the conditions that are associated with Cardiac valve disease:

Cardiac valve disease (764 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lovastatin (the active ingredients of Lovastatin) and Lovastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.