Lovastatin and Major depression - a phase IV clinical study of FDA data

Summary:

Major depression is reported as a side effect among people who take Lovastatin (lovastatin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lisinopril, and have Depression.

The phase IV clinical study analyzes which people have Major depression when taking Lovastatin. It is created by eHealthMe based on reports of 31,864 people who have side effects when taking Lovastatin from the FDA, and is updated regularly.

What is Lovastatin?

Lovastatin has active ingredients of lovastatin. It is often used in high blood cholesterol. eHealthMe is studying from 33,048 Lovastatin users. Check the latest studies of Lovastatin.

What is Major depression?

Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings) is found to be associated with 804 drugs and 1,475 conditions by eHealthMe. Check the latest studies of Major depression.

On Jul, 07, 2026

31,864 people reported to have side effects when taking Lovastatin.
Among them, 32 people (0.1%) have Major depression.

Could Lovastatin cause Major depression?

Among these 32 people:

How long have people been on Lovastatin when they have Major depression? *

What is the gender of people who have Major depression when taking Lovastatin? *

female: 75 %
male: 25 %

What is the age of people who have Major depression when taking Lovastatin? *

What are other drugs people take besides Lovastatin? *

Omeprazole: 7 people, 21.88%
Levothroid: 7 people, 21.88%
Metformin: 7 people, 21.88%
Lisinopril: 7 people, 21.88%
Humira: 5 people, 15.62%
Glipizide: 5 people, 15.62%
Fluoxetine: 5 people, 15.62%
Simvastatin: 5 people, 15.62%
Fluvastatin: 5 people, 15.62%
Imipramine Hydrochloride: 4 people, 12.50%

What are other side effects people have besides Major depression? *

Stress And Anxiety: 17 people, 53.12%
Depression: 10 people, 31.25%
Suicidal Ideation: 10 people, 31.25%
Drug Hypersensitivity: 9 people, 28.12%
Memory Loss: 9 people, 28.12%
Headache (pain in head): 8 people, 25.00%
Coordination Abnormal (abnormal movement): 8 people, 25.00%
Diarrhea: 7 people, 21.88%
Night Sweats (sweating in night): 7 people, 21.88%
Restless Leg Syndrome (a powerful urge to move your legs): 7 people, 21.88%

What are the existing conditions these people have? *

Depression: 12 people, 37.50%
Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 21.88%
Stress And Anxiety: 6 people, 18.75%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 18.75%
Diabetes: 6 people, 18.75%
Lipid Metabolism Disorder (genetic disorders are caused by errors in fatty acid metabolism): 5 people, 15.62%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 5 people, 15.62%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 15.62%
Thyroid Diseases: 4 people, 12.50%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Lovastatin and have Major depression?

- Check whether Major depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lovastatin:

Lovastatin (33,048 reports)

Major depression treatments and more:

Major depression (44,979 reports)

Browse all side effects of Lovastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Major depression:

Major depression (804 drugs)

Browse all the conditions that are associated with Major depression:

Major depression (1,475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lovastatin (the active ingredients of Lovastatin) and Lovastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.