Lovenox and Epidermal necrosis - a phase IV clinical study of FDA data

Summary:

Epidermal necrosis is reported as a side effect among people who take Lovenox (enoxaparin sodium), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Apidra, and have Pain.

The phase IV clinical study analyzes which people have Epidermal necrosis when taking Lovenox. It is created by eHealthMe based on reports of 47,547 people who have side effects when taking Lovenox from the FDA, and is updated regularly.

What is Lovenox?

Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.

What is Epidermal necrosis?

Epidermal necrosis (skin condition that is usually caused by a reaction to drugs) is found to be associated with 140 drugs and 320 conditions by eHealthMe. Check the latest studies of Epidermal necrosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

47,547 people reported to have side effects when taking Lovenox.
Among them, 16 people (0.03%) have Epidermal necrosis.

Among these 16 people:

How long have people been on Lovenox when they have Epidermal necrosis? *

What is the gender of people who have Epidermal necrosis when taking Lovenox? *

female: 25 %
male: 75 %

What is the age of people who have Epidermal necrosis when taking Lovenox? *

What are other drugs people take besides Lovenox? *

What are other side effects people have besides Epidermal necrosis? *

Erysipelas (bacterial skin infection): 8 people, 50.00%
Eschar (dead tissue that falls off (sheds) from healthy skin): 8 people, 50.00%
Diabetic Bullosis (bullous disease of diabetes (bullosis diabeticorum) is a distinct, spontaneous, noninflammatory, blistering condition of acral skin): 8 people, 50.00%
Toxic Skin Eruption (skin breakdown due to toxic substance): 5 people, 31.25%
Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 4 people, 25.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 18.75%
General Physical Health Deterioration (weak health status): 3 people, 18.75%
Fever: 3 people, 18.75%
Lung Infection: 2 people, 12.50%
Troponin T Increased: 2 people, 12.50%

What are the existing conditions these people have? *

Pain: 10 people, 62.50%
Type 2 Diabetes: 8 people, 50.00%
Diabetic Foot: 8 people, 50.00%
Lung Infection: 3 people, 18.75%
Stress And Anxiety: 2 people, 12.50%
Insomnia (sleeplessness): 2 people, 12.50%
Respiratory Disorder (respiratory disease): 1 person, 6.25%
Pneumonia: 1 person, 6.25%
Ill-Defined Disorder: 1 person, 6.25%
Hodgkin's Lymphoma (cancer originating from white blood cells): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lovenox and have Epidermal necrosis?

- Check whether Epidermal necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lovenox:

Lovenox (48,149 reports)

Browse all side effects of Lovenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Epidermal necrosis:

Epidermal necrosis (140 drugs)

Browse all the conditions that are associated with Epidermal necrosis:

Epidermal necrosis (320 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on enoxaparin sodium (the active ingredients of Lovenox) and Lovenox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.