Lovenox and Injection site induration - a phase IV clinical study of FDA data

Summary:

Injection site induration is reported as a side effect among people who take Lovenox (enoxaparin sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have Thrombosis.

The phase IV clinical study analyzes which people have Injection site induration when taking Lovenox. It is created by eHealthMe based on reports of 47,547 people who have side effects when taking Lovenox from the FDA, and is updated regularly.

What is Lovenox?

Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.

What is Injection site induration?

Injection site induration is found to be associated with 554 drugs and 627 conditions by eHealthMe. Check the latest studies of Injection site induration.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

47,547 people reported to have side effects when taking Lovenox.
Among them, 39 people (0.08%) have Injection site induration.

Could Lovenox cause Injection site induration?

Among these 39 people:

How long have people been on Lovenox when they have Injection site induration? *

  • < 1 month: 55.56 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 11.11 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Injection site induration when taking Lovenox? *

  • female: 68.42 %
  • male: 31.58 %

What is the age of people who have Injection site induration when taking Lovenox? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.41 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 7.41 %
  • 60+: 74.07 %

What are other drugs people take besides Lovenox? *

  1. Temodar: 4 people, 10.26%
  2. Keppra: 4 people, 10.26%
  3. Coumadin: 4 people, 10.26%
  4. Heparin: 3 people, 7.69%
  5. Xarelto: 2 people, 5.13%
  6. Vitamin E: 2 people, 5.13%
  7. Celexa: 2 people, 5.13%
  8. Levothyroxine Sodium: 2 people, 5.13%
  9. Eliquis: 2 people, 5.13%
  10. Melilot: 2 people, 5.13%

What are other side effects people have besides Injection site induration? *

  1. Injection Site Pain: 17 people, 43.59%
  2. Injection Site Bruising: 10 people, 25.64%
  3. Injection Site Erythema (redness at injection site): 9 people, 23.08%
  4. Head Injury: 7 people, 17.95%
  5. Injection Site Mass: 6 people, 15.38%
  6. Pain: 5 people, 12.82%
  7. Injection Site Swelling: 5 people, 12.82%
  8. Injection Site Haemorrhage (bleeding from injection site): 5 people, 12.82%
  9. Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 10.26%
  10. Rashes (redness): 4 people, 10.26%

What are the existing conditions these people have? *

  1. Thrombosis (formation of a blood clot inside a blood vessel): 5 people, 12.82%
  2. Venous Thrombosis (blood clot (thrombus) that forms within a vein): 2 people, 5.13%
  3. Pain: 2 people, 5.13%
  4. Blood Thyroid Stimulating Hormone Increased: 2 people, 5.13%
  5. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 2.56%
  6. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 2.56%
  7. Premature Delivery: 1 person, 2.56%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.56%
  9. Migraine (headache): 1 person, 2.56%
  10. Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Lovenox and have Injection site induration?

- Check whether Injection site induration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lovenox:

Injection site induration treatments and more:

How severe was Injection site induration and when was it recovered:

Expand to all the drugs that have ingredients of enoxaparin sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lovenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site induration:

Browse all the conditions that are associated with Injection site induration:


How the study uses the data?

The study uses data from the FDA. It is based on enoxaparin sodium (the active ingredients of Lovenox) and Lovenox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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