Lucentis and Fluid overload - a phase IV clinical study of FDA data

Summary:

Fluid overload is reported as a side effect among people who take Lucentis (ranibizumab), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Amlodipine, and have Diabetic retinal oedema.

The phase IV clinical study analyzes which people have Fluid overload when taking Lucentis. It is created by eHealthMe based on reports of 25,577 people who have side effects when taking Lucentis from the FDA, and is updated regularly.

What is Lucentis?

Lucentis has active ingredients of ranibizumab. It is often used in macular degeneration. eHealthMe is studying from 25,647 Lucentis users. Check the latest studies of Lucentis.

What is Fluid overload?

Fluid overload (too much fluid in the blood) is found to be associated with 1,090 drugs and 1,045 conditions by eHealthMe. Check the latest studies of Fluid overload.

On Dec, 27, 2025

25,577 people reported to have side effects when taking Lucentis.
Among them, 10 people (0.04%) have Fluid overload.

Among these 10 people:

How long have people been on Lucentis when they have Fluid overload? *

What is the gender of people who have Fluid overload when taking Lucentis? *

female: 44.44 %
male: 55.56 %

What is the age of people who have Fluid overload when taking Lucentis? *

What are other drugs people take besides Lucentis? *

What are other side effects people have besides Fluid overload? *

Pneumonia: 5 people, 50.00%
Dyspnea (difficult or laboured breathing): 5 people, 50.00%
Dizziness: 5 people, 50.00%
Renal Impairment (severely reduced kidney function): 4 people, 40.00%
Peripheral Swelling: 4 people, 40.00%
The Flu (the flu is caused by an influenza virus): 4 people, 40.00%
High Blood Pressure: 4 people, 40.00%
Rashes (redness): 4 people, 40.00%
Renal Disorder (kidney disease): 4 people, 40.00%
Joint Swelling: 3 people, 30.00%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 30.00%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 3 people, 30.00%
Diabetes: 2 people, 20.00%
High Blood Cholesterol: 2 people, 20.00%
Vitamin D Decreased: 1 person, 10.00%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 1 person, 10.00%
Chest Pain: 1 person, 10.00%
Constipation: 1 person, 10.00%
Diabetic Eye Disease: 1 person, 10.00%
Eye Haemorrhage (bleeding in the eye): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lucentis and have Fluid overload?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lucentis:

Lucentis (25,647 reports)

Fluid overload treatments and more:

Fluid overload (20,385 reports)

Browse all side effects of Lucentis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fluid overload:

Fluid overload (1,090 drugs)

Browse all the conditions that are associated with Fluid overload:

Fluid overload (1,045 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranibizumab (the active ingredients of Lucentis) and Lucentis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.