Lucentis and Musculoskeletal stiffness - a phase IV clinical study of FDA data

Summary:

Musculoskeletal stiffness is reported as a side effect among people who take Lucentis (ranibizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Avastin, and have Age-related macular degeneration.

The phase IV clinical study analyzes which people have Musculoskeletal stiffness when taking Lucentis. It is created by eHealthMe based on reports of 25,577 people who have side effects when taking Lucentis from the FDA, and is updated regularly.

What is Lucentis?

Lucentis has active ingredients of ranibizumab. It is often used in macular degeneration. eHealthMe is studying from 25,647 Lucentis users. Check the latest studies of Lucentis.

What is Musculoskeletal stiffness?

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves) is found to be associated with 1,960 drugs and 1,916 conditions by eHealthMe. Check the latest studies of Musculoskeletal stiffness.

On Aug, 08, 2026

25,577 people reported to have side effects when taking Lucentis.
Among them, 32 people (0.13%) have Musculoskeletal stiffness.

Could Lucentis cause Musculoskeletal stiffness?

Among these 32 people:

How long have people been on Lucentis when they have Musculoskeletal stiffness? *

What is the gender of people who have Musculoskeletal stiffness when taking Lucentis? *

female: 84.38 %
male: 15.62 %

What is the age of people who have Musculoskeletal stiffness when taking Lucentis? *

What are other drugs people take besides Lucentis? *

What are other side effects people have besides Musculoskeletal stiffness? *

Headache (pain in head): 8 people, 25.00%
Back Pain: 8 people, 25.00%
Pain: 8 people, 25.00%
Weakness: 7 people, 21.88%
Stress And Anxiety: 7 people, 21.88%
Memory Loss: 7 people, 21.88%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 7 people, 21.88%
Joint Pain: 7 people, 21.88%
High Blood Pressure: 7 people, 21.88%
Visual Acuity Reduced (reduced clearness of vision): 6 people, 18.75%

What are the existing conditions these people have? *

Age-Related Macular Degeneration: 8 people, 25.00%
Eye Inflammation: 4 people, 12.50%
Stress And Anxiety: 3 people, 9.38%
Retinopathy (acute damage to the retina of the eye): 3 people, 9.38%
Vaginal Infection: 3 people, 9.38%
High Blood Pressure: 3 people, 9.38%
Diabetes: 2 people, 6.25%
Arteritis (inflammation of the walls of arteries): 2 people, 6.25%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 6.25%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lucentis and have Musculoskeletal stiffness?

- Check whether Musculoskeletal stiffness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lucentis:

Lucentis (25,647 reports)

Browse all side effects of Lucentis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Musculoskeletal stiffness:

Musculoskeletal stiffness (1,960 drugs)

Browse all the conditions that are associated with Musculoskeletal stiffness:

Musculoskeletal stiffness (1,916 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranibizumab (the active ingredients of Lucentis) and Lucentis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.