Lucentis and Sciatica aggravated - a phase IV clinical study of FDA data

Summary:

Sciatica aggravated is reported as a side effect among people who take Lucentis (ranibizumab), especially for people who are female, 60+ old, also take Lyrica, and have Age-related macular degeneration.

The phase IV clinical study analyzes which people have Sciatica aggravated when taking Lucentis. It is created by eHealthMe based on reports of 25,577 people who have side effects when taking Lucentis from the FDA, and is updated regularly.

What is Lucentis?

Lucentis has active ingredients of ranibizumab. It is often used in macular degeneration. eHealthMe is studying from 25,647 Lucentis users. Check the latest studies of Lucentis.

What is Sciatica aggravated?

Sciatica aggravated (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,061 drugs and 403 conditions by eHealthMe. Check the latest studies of Sciatica aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

25,577 people reported to have side effects when taking Lucentis.
Among them, 16 people (0.06%) have Sciatica aggravated.

Could Lucentis cause Sciatica aggravated?

Among these 16 people:

What is the gender of people who have Sciatica aggravated when taking Lucentis? *

female: 81.25 %
male: 18.75 %

What is the age of people who have Sciatica aggravated when taking Lucentis? *

What are other drugs people take besides Lucentis? *

What are other side effects people have besides Sciatica aggravated? *

Visual Acuity Reduced (reduced clearness of vision): 6 people, 37.50%
Pain: 5 people, 31.25%
Abdominal Pain Upper: 4 people, 25.00%
Visual Impairment: 4 people, 25.00%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 25.00%
Migraine With Aura (headache with vision weakness): 3 people, 18.75%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 18.75%
Dry Eyes (lack of adequate tears): 3 people, 18.75%
Gait Disturbance: 3 people, 18.75%
Cataract (clouding of the lens inside the eye): 3 people, 18.75%

What are the existing conditions these people have? *

Age-Related Macular Degeneration: 4 people, 25.00%
Pain: 3 people, 18.75%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 18.75%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 3 people, 18.75%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 18.75%
High Blood Pressure: 1 person, 6.25%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 6.25%
Asthma: 1 person, 6.25%
Breast Cancer: 1 person, 6.25%
Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lucentis and have Sciatica aggravated?

- Check whether Sciatica aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lucentis:

Lucentis (25,647 reports)

Browse all side effects of Lucentis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica aggravated:

Sciatica aggravated (1,061 drugs)

Browse all the conditions that are associated with Sciatica aggravated:

Sciatica aggravated (403 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranibizumab (the active ingredients of Lucentis) and Lucentis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.