Lumify and Instillation site pruritus - a phase IV clinical study of FDA data

Summary:

Instillation site pruritus is reported as a side effect among people who take Lumify (brimonidine tartrate), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Alaway, and have Ocular hyperaemia.

The phase IV clinical study analyzes which people have Instillation site pruritus when taking Lumify. It is created by eHealthMe based on reports of 3,670 people who have side effects when taking Lumify from the FDA, and is updated regularly.

What is Lumify?

Lumify has active ingredients of brimonidine tartrate. eHealthMe is studying from 3,670 Lumify users. Check the latest studies of Lumify.

What is Instillation site pruritus?

Instillation site pruritus (severe itching at instillation site) is found to be associated with 13 drugs and 56 conditions by eHealthMe. Check the latest studies of Instillation site pruritus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

3,670 people reported to have side effects when taking Lumify.
Among them, 22 people (0.6%) have Instillation site pruritus.

Could Lumify cause Instillation site pruritus?

Among these 22 people:

How long have people been on Lumify when they have Instillation site pruritus? *

What is the gender of people who have Instillation site pruritus when taking Lumify? *

female: 70 %
male: 30 %

What is the age of people who have Instillation site pruritus when taking Lumify? *

What are other drugs people take besides Lumify? *

Zioptan: 1 person, 4.55%
Alaway: 1 person, 4.55%

What are other side effects people have besides Instillation site pruritus? *

Instillation Site Erythema (instillation site redness): 5 people, 22.73%
Instillation Site Pain: 4 people, 18.18%
Instillation Site Irritation: 3 people, 13.64%
Instillation Site Lacrimation: 3 people, 13.64%
Vision Blurred: 2 people, 9.09%
Headache (pain in head): 1 person, 4.55%
Drug Hypersensitivity: 1 person, 4.55%
Dyspnea (difficult or laboured breathing): 1 person, 4.55%
Eye Disorder: 1 person, 4.55%
Eye Haemorrhage (bleeding in the eye): 1 person, 4.55%

What are the existing conditions these people have? *

Ocular Hyperaemia (an abnormally large amount of blood in eye): 9 people, 40.91%
Dry Eyes (lack of adequate tears): 2 people, 9.09%
Eye Pruritus (eye itching): 1 person, 4.55%
Eye Irritation: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Lumify and have Instillation site pruritus?

- Check whether Instillation site pruritus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lumify:

Lumify (3,670 reports)

Browse all side effects of Lumify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Instillation site pruritus:

Instillation site pruritus (13 drugs)

Browse all the conditions that are associated with Instillation site pruritus:

Instillation site pruritus (56 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brimonidine tartrate (the active ingredients of Lumify) and Lumify (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.