Lumigan and Asthenopia - a phase IV clinical study of FDA data

Summary:

Asthenopia is reported as a side effect among people who take Lumigan (bimatoprost), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Combigan, and have Intraocular pressure increased.

The phase IV clinical study analyzes which people have Asthenopia when taking Lumigan. It is created by eHealthMe based on reports of 20,141 people who have side effects when taking Lumigan from the FDA, and is updated regularly.

What is Lumigan?

Lumigan has active ingredients of bimatoprost. It is often used in glaucoma. eHealthMe is studying from 20,478 Lumigan users. Check the latest studies of Lumigan.

What is Asthenopia?

Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem) is found to be associated with 467 drugs and 627 conditions by eHealthMe. Check the latest studies of Asthenopia.



On Jul, 14, 2026

20,141 people reported to have side effects when taking Lumigan.
Among them, 50 people (0.25%) have Asthenopia.

Could Lumigan cause Asthenopia?

Among these 50 people:

How long have people been on Lumigan when they have Asthenopia? *

  • < 1 month: 80 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Asthenopia when taking Lumigan? *

  • female: 70 %
  • male: 30 %

What is the age of people who have Asthenopia when taking Lumigan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 6.67 %
  • 60+: 93.33 %

What are other drugs people take besides Lumigan? *

  1. Combigan: 5 people, 10.00%
  2. Diclofenac: 4 people, 8.00%
  3. Azilect: 4 people, 8.00%
  4. Rytary: 4 people, 8.00%
  5. Seroquel: 4 people, 8.00%
  6. Azopt: 4 people, 8.00%
  7. Nuplazid: 4 people, 8.00%
  8. Alphagan P: 4 people, 8.00%
  9. Gralise: 4 people, 8.00%
  10. Restasis: 3 people, 6.00%

What are other side effects people have besides Asthenopia? *

  1. Eye Pain: 13 people, 26.00%
  2. Vision Blurred: 12 people, 24.00%
  3. Eye Irritation: 9 people, 18.00%
  4. Fatigue (feeling of tiredness): 9 people, 18.00%
  5. Ocular Hyperaemia (an abnormally large amount of blood in eye): 7 people, 14.00%
  6. Malaise (a feeling of general discomfort or uneasiness): 6 people, 12.00%
  7. Drowsiness: 6 people, 12.00%
  8. Ocular Discomfort (a generic expression when there is lack of ease in/about the eyes): 5 people, 10.00%
  9. Rhinorrhea (watery mucus discharge from the nose): 5 people, 10.00%
  10. Upper Respiratory Tract Infection: 5 people, 10.00%

What are the existing conditions these people have? *

  1. Intraocular Pressure Increased: 11 people, 22.00%
  2. Dry Eyes (lack of adequate tears): 5 people, 10.00%
  3. Hallucinations (sensations that appear real but are created by your mind): 4 people, 8.00%
  4. Psychotic Disorder: 4 people, 8.00%
  5. Delusion (a false belief or opinion): 4 people, 8.00%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.00%
  7. Sleep Disorder: 2 people, 4.00%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 4.00%
  9. Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 2 people, 4.00%
  10. Malignant Melanoma (skin cancer rises from melancytes): 2 people, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lumigan and have Asthenopia?

- Check whether Asthenopia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lumigan:

Asthenopia treatments and more:

How severe was Asthenopia and when was it recovered:

Expand to all the drugs that have ingredients of bimatoprost:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lumigan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Asthenopia:

Browse all the conditions that are associated with Asthenopia:


How the study uses the data?

The study uses data from the FDA. It is based on bimatoprost (the active ingredients of Lumigan) and Lumigan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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