Lumigan and Knee joint replacement - a phase IV clinical study of FDA data

Summary:

Knee joint replacement is reported as a side effect among people who take Lumigan (bimatoprost), especially for people who are female, 60+ old, also take Lantus, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Knee joint replacement when taking Lumigan. It is created by eHealthMe based on reports of 20,141 people who have side effects when taking Lumigan from the FDA, and is updated regularly.

What is Lumigan?

Lumigan has active ingredients of bimatoprost. It is often used in glaucoma. eHealthMe is studying from 20,478 Lumigan users. Check the latest studies of Lumigan.

What is Knee joint replacement?

Knee joint replacement is found to be associated with 946 drugs and 1,232 conditions by eHealthMe. Check the latest studies of Knee joint replacement.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

20,141 people reported to have side effects when taking Lumigan.
Among them, 31 people (0.15%) have Knee joint replacement.

Could Lumigan cause Knee joint replacement?

Among these 31 people:

What is the gender of people who have Knee joint replacement when taking Lumigan? *

female: 74.19 %
male: 25.81 %

What is the age of people who have Knee joint replacement when taking Lumigan? *

What are other drugs people take besides Lumigan? *

What are other side effects people have besides Knee joint replacement? *

Pain In Extremity: 12 people, 38.71%
Joint Pain: 9 people, 29.03%
Cataract (clouding of the lens inside the eye): 7 people, 22.58%
Blood Glucose Increased: 7 people, 22.58%
Renal Disorder (kidney disease): 6 people, 19.35%
Injection Site Bruising: 6 people, 19.35%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 6 people, 19.35%
Gait Disturbance: 6 people, 19.35%
Carpal Tunnel Decompression: 6 people, 19.35%
Injection Site Haemorrhage (bleeding from injection site): 6 people, 19.35%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 25.81%
Type 2 Diabetes: 6 people, 19.35%
Pain: 4 people, 12.90%
High Blood Cholesterol: 3 people, 9.68%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 9.68%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 6.45%
Hypothalamo-Pituitary Disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function): 2 people, 6.45%
Osteoporosis (bones weak and more likely to break): 2 people, 6.45%
Prostatomegaly (enlargement of the prostate): 2 people, 6.45%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Lumigan and have Knee joint replacement?

- Check whether Knee joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lumigan:

Lumigan (20,478 reports)

Browse all side effects of Lumigan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Knee joint replacement:

Knee joint replacement (946 drugs)

Browse all the conditions that are associated with Knee joint replacement:

Knee joint replacement (1,232 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bimatoprost (the active ingredients of Lumigan) and Lumigan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.