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Lunesta and Shoulder operation - a phase IV clinical study of FDA data

Summary:

Shoulder operation is reported as a side effect among people who take Lunesta (eszopiclone), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ambien, and have Metastases to bone.

The phase IV clinical study analyzes which people have Shoulder operation when taking Lunesta. It is created by eHealthMe based on reports of 25,141 people who have side effects when taking Lunesta from the FDA, and is updated regularly.

What is Lunesta?

Lunesta has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 26,936 Lunesta users. Check the latest studies of Lunesta.

What is Shoulder operation?

Shoulder operation is found to be associated with 390 drugs and 290 conditions by eHealthMe. Check the latest studies of Shoulder operation.

On Jul, 21, 2026

25,141 people reported to have side effects when taking Lunesta.
Among them, 16 people (0.06%) have Shoulder operation.

Could Lunesta cause Shoulder operation?

Among these 16 people:

How long have people been on Lunesta when they have Shoulder operation? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Shoulder operation when taking Lunesta? *

  • female: 6.25 %
  • male: 93.75 %

What is the age of people who have Shoulder operation when taking Lunesta? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 27.27 %
  • 60+: 72.73 %

What are other drugs people take besides Lunesta? *

  1. Ambien: 12 people, 75.00%
  2. Celebrex: 10 people, 62.50%
  3. Zometa: 9 people, 56.25%
  4. Spiriva: 9 people, 56.25%
  5. Accuneb: 9 people, 56.25%
  6. Eligard: 9 people, 56.25%
  7. Folic Acid: 9 people, 56.25%
  8. Mucinex: 9 people, 56.25%
  9. Percocet: 9 people, 56.25%
  10. Protonix: 9 people, 56.25%

What are other side effects people have besides Shoulder operation? *

  1. Spinal Osteoarthritis (joint cartilage loss in spine): 10 people, 62.50%
  2. Weakness: 9 people, 56.25%
  3. Injury: 9 people, 56.25%
  4. Metastases To Bone (cancer spreads to bone): 9 people, 56.25%
  5. Radiculitis Lumbosacral (inflammation of nerve root at labosacral vertebrea): 9 people, 56.25%
  6. Joint Injury: 9 people, 56.25%
  7. Joint Effusion (presence of extra fluid in joint covering): 9 people, 56.25%
  8. Jaw Disorder (jaw disease): 9 people, 56.25%
  9. Cyst (a closed sac): 9 people, 56.25%
  10. Spinal Column Stenosis (narrowing of spinal column): 9 people, 56.25%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 9 people, 56.25%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 25.00%
  3. Pain: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lunesta and have Shoulder operation?

- Check whether Shoulder operation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lunesta:

Shoulder operation treatments and more:

How severe was Shoulder operation and when was it recovered:

Expand to all the drugs that have ingredients of eszopiclone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lunesta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shoulder operation:

Browse all the conditions that are associated with Shoulder operation:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone (the active ingredients of Lunesta) and Lunesta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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