Lupron depot and Pain - a phase IV clinical study of FDA data

Summary:

Pain is reported as a side effect among people who take Lupron depot (leuprolide acetate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Calcium, and have Uterine leiomyoma.

The phase IV clinical study analyzes which people have Pain when taking Lupron depot. It is created by eHealthMe based on reports of 26,734 people who have side effects when taking Lupron depot from the FDA, and is updated regularly.

What is Lupron depot?

Lupron depot has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 27,036 Lupron depot users. Check the latest studies of Lupron depot.

What is Pain?

Pain is found to be associated with 3,823 drugs and 5,859 conditions by eHealthMe. Check the latest studies of Pain.



On May, 14, 2026

26,734 people reported to have side effects when taking Lupron depot.
Among them, 1,400 people (5.24%) have Pain.

Could Lupron depot cause Pain?

Among these 1,400 people:

How long have people been on Lupron depot when they have Pain? *

What is the gender of people who have Pain when taking Lupron depot? *

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What is the age of people who have Pain when taking Lupron depot? *

What are other drugs people take besides Lupron depot? *

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What are other side effects people have besides Pain? *

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What are the existing conditions these people have? *

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* Approximation only. Some reports may have incomplete information.

Do you take Lupron depot and have Pain?

- Check whether Pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lupron depot:

Pain treatments and more:

  • Pain (1,140,594 reports)

How severe was Pain and when was it recovered:

Expand to all the drugs that have ingredients of leuprolide acetate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lupron depot:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain:

  • Pain (3,823 drugs)

Browse all the conditions that are associated with Pain:

  • Pain (5,859 conditions)

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on leuprolide acetate (the active ingredients of Lupron depot) and Lupron depot (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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