Luvox and Flat affect - a phase IV clinical study of FDA data

Summary:

Flat affect is reported as a side effect among people who take Luvox (fluvoxamine maleate), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Norvasc, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Flat affect when taking Luvox. It is created by eHealthMe based on reports of 12,486 people who have side effects when taking Luvox from the FDA, and is updated regularly.

What is Luvox?

Luvox has active ingredients of fluvoxamine maleate. It is often used in obsessive-compulsive disorder. eHealthMe is studying from 13,439 Luvox users. Check the latest studies of Luvox.

What is Flat affect?

Flat affect (absence of emotional response to a situation) is found to be associated with 294 drugs and 458 conditions by eHealthMe. Check the latest studies of Flat affect.



On May, 10, 2026

12,486 people reported to have side effects when taking Luvox.
Among them, 10 people (0.08%) have Flat affect.

Could Luvox cause Flat affect?

Among these 10 people:

How long have people been on Luvox when they have Flat affect? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Flat affect when taking Luvox? *

  • female: 55.56 %
  • male: 44.44 %

What is the age of people who have Flat affect when taking Luvox? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 57.14 %
  • 30-39: 0.0 %
  • 40-49: 14.29 %
  • 50-59: 0.0 %
  • 60+: 28.57 %

What are other drugs people take besides Luvox? *

  1. Spiriva: 3 people, 30.00%
  2. Ventolin: 3 people, 30.00%
  3. Norvasc: 3 people, 30.00%
  4. Zyprexa: 2 people, 20.00%
  5. Prednisolone: 2 people, 20.00%
  6. Lamictal: 2 people, 20.00%
  7. Chantix: 2 people, 20.00%
  8. Folic Acid: 1 person, 10.00%
  9. Disopyramide Phosphate: 1 person, 10.00%
  10. Erythromycin: 1 person, 10.00%

What are other side effects people have besides Flat affect? *

  1. Feeling Abnormal: 5 people, 50.00%
  2. Suicidal Ideation: 4 people, 40.00%
  3. Confusional State: 3 people, 30.00%
  4. Weakness: 3 people, 30.00%
  5. Insomnia (sleeplessness): 3 people, 30.00%
  6. Irritability: 2 people, 20.00%
  7. Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 2 people, 20.00%
  8. Abdominal Pain: 2 people, 20.00%
  9. Panic Disorder: 2 people, 20.00%
  10. Mood Swings (an extreme or rapid change in mood): 2 people, 20.00%

What are the existing conditions these people have? *

  1. Quit Smoking: 3 people, 30.00%
  2. High Blood Pressure: 3 people, 30.00%
  3. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 30.00%
  4. Psychotic Disorder: 1 person, 10.00%
  5. Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 10.00%
  6. Pain: 1 person, 10.00%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 10.00%
  8. Indigestion: 1 person, 10.00%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 10.00%
  10. Constipation: 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Luvox and have Flat affect?

- Check whether Flat affect is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Luvox:

Flat affect treatments and more:

How severe was Flat affect and when was it recovered:

Expand to all the drugs that have ingredients of fluvoxamine maleate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Luvox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flat affect:

Browse all the conditions that are associated with Flat affect:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluvoxamine maleate (the active ingredients of Luvox) and Luvox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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