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Lynparza and Hyponatremia - a phase IV clinical study of FDA data

Summary:

Hyponatremia is reported as a side effect among people who take Lynparza (olaparib), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Tylenol, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Hyponatremia when taking Lynparza. It is created by eHealthMe based on reports of 12,309 people who have side effects when taking Lynparza from the FDA, and is updated regularly.

What is Lynparza?

Lynparza has active ingredients of olaparib. eHealthMe is studying from 12,322 Lynparza users. Check the latest studies of Lynparza.

What is Hyponatremia?

Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration) is found to be associated with 1,940 drugs and 2,277 conditions by eHealthMe. Check the latest studies of Hyponatremia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

12,309 people reported to have side effects when taking Lynparza.
Among them, 17 people (0.14%) have Hyponatremia.

Could Lynparza cause Hyponatremia?

Among these 17 people:

How long have people been on Lynparza when they have Hyponatremia? *

  • < 1 month: 11.11 %
  • 1 - 6 months: 55.56 %
  • 6 - 12 months: 22.22 %
  • 1 - 2 years: 11.11 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyponatremia when taking Lynparza? *

  • female: 88.24 %
  • male: 11.76 %

What is the age of people who have Hyponatremia when taking Lynparza? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 6.67 %
  • 60+: 93.33 %

What are other drugs people take besides Lynparza? *

  1. Faslodex: 2 people, 11.76%
  2. Palbociclib: 2 people, 11.76%
  3. Tylenol: 2 people, 11.76%
  4. Erythromycin: 1 person, 5.88%
  5. Edarbyclor: 1 person, 5.88%
  6. Doxycycline: 1 person, 5.88%
  7. Doxil: 1 person, 5.88%
  8. Creon: 1 person, 5.88%
  9. Cipro: 1 person, 5.88%
  10. Benadryl: 1 person, 5.88%

What are other side effects people have besides Hyponatremia? *

  1. Hypokalemia (low potassium): 6 people, 35.29%
  2. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 35.29%
  3. Pleural Effusion (water on the lungs): 5 people, 29.41%
  4. Nausea (feeling of having an urge to vomit): 5 people, 29.41%
  5. Rashes (redness): 5 people, 29.41%
  6. Anaemia (lack of blood): 4 people, 23.53%
  7. Dyspnea (difficult or laboured breathing): 4 people, 23.53%
  8. Pericardial Effusion (fluid around the heart): 4 people, 23.53%
  9. Oedema Peripheral (superficial swelling): 3 people, 17.65%
  10. Blood Sodium Decreased: 3 people, 17.65%

What are the existing conditions these people have? *

  1. Ovarian Cancer (cancer of ovary): 5 people, 29.41%
  2. Mesothelioma (rare type of cancer that occurs in the thin layer of cells lining the body's internal organs, known as the mesothelium): 2 people, 11.76%
  3. Breast Cancer Metastatic: 2 people, 11.76%
  4. Stress And Anxiety: 1 person, 5.88%
  5. Pancreatic Carcinoma (pancreatic cancer): 1 person, 5.88%
  6. Pain: 1 person, 5.88%
  7. Ovarian Cancer Stage Iii: 1 person, 5.88%
  8. Ovarian Cancer Metastatic (cancer of ovary spreads to other organ or parts): 1 person, 5.88%
  9. Neoplasm Malignant (cancer tumour): 1 person, 5.88%
  10. Nausea And Vomiting: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Lynparza and have Hyponatremia?

- Check whether Hyponatremia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lynparza:

Hyponatremia treatments and more:

How severe was Hyponatremia and when was it recovered:

Expand to all the drugs that have ingredients of olaparib:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lynparza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatremia:

Browse all the conditions that are associated with Hyponatremia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on olaparib (the active ingredients of Lynparza) and Lynparza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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