Lysine and Overdose - a phase IV clinical study of FDA data

Summary:

Overdose is reported as a side effect among people who take Lysine (lysine), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Threonine, and have Systemic lupus erythematosus.

The phase IV clinical study analyzes which people have Overdose when taking Lysine. It is created by eHealthMe based on reports of 15,985 people who have side effects when taking Lysine from the FDA, and is updated regularly.

What is Lysine?

Lysine has active ingredients of lysine. It is often used in herpes labialis (oral herpes simplex). eHealthMe is studying from 16,524 Lysine users. Check the latest studies of Lysine.

What is Overdose?

Overdose is found to be associated with 2,220 drugs and 2,472 conditions by eHealthMe. Check the latest studies of Overdose.



On Jul, 11, 2026

15,985 people reported to have side effects when taking Lysine.
Among them, 52 people (0.33%) have Overdose.

Could Lysine cause Overdose?

Among these 52 people:

How long have people been on Lysine when they have Overdose? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Overdose when taking Lysine? *

  • female: 43.9 %
  • male: 56.1 %

What is the age of people who have Overdose when taking Lysine? *

  • 0-1: 5.56 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.56 %
  • 30-39: 2.78 %
  • 40-49: 11.11 %
  • 50-59: 55.56 %
  • 60+: 19.44 %

What are other drugs people take besides Lysine? *

  1. Valine: 21 people, 40.38%
  2. Phenylalanine: 21 people, 40.38%
  3. Glutamic Acid: 21 people, 40.38%
  4. Histidine: 21 people, 40.38%
  5. Threonine: 21 people, 40.38%
  6. Potassium Chloride: 17 people, 32.69%
  7. Activated Charcoal: 17 people, 32.69%
  8. Methylene Blue: 17 people, 32.69%
  9. Glucagon: 17 people, 32.69%
  10. Aspartic Acid: 17 people, 32.69%

What are other side effects people have besides Overdose? *

  1. Hypotension (abnormally low blood pressure): 21 people, 40.38%
  2. Cardiac Arrest: 21 people, 40.38%
  3. Coma Scale Abnormal: 21 people, 40.38%
  4. Compartment Syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels): 21 people, 40.38%
  5. Lactic Acidosis (low ph in body tissues): 21 people, 40.38%
  6. Intestinal Obstruction: 21 people, 40.38%
  7. Pulse Absent: 21 people, 40.38%
  8. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 21 people, 40.38%
  9. Bradycardia (abnormally slow heart action): 21 people, 40.38%
  10. Hyperkalemia (damage to or disease of the kidney): 21 people, 40.38%

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 10 people, 19.23%
  2. High Blood Cholesterol: 4 people, 7.69%
  3. Pain: 4 people, 7.69%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.77%
  5. High Blood Pressure: 3 people, 5.77%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 3.85%
  7. Hair Loss: 2 people, 3.85%
  8. Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 3.85%
  9. Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs): 2 people, 3.85%
  10. Osteoporosis (bones weak and more likely to break): 2 people, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Lysine and have Overdose?

- Check whether Overdose is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lysine:

Overdose treatments and more:

How severe was Overdose and when was it recovered:

Expand to all the drugs that have ingredients of lysine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lysine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Overdose:

Browse all the conditions that are associated with Overdose:


How the study uses the data?

The study uses data from the FDA. It is based on lysine (the active ingredients of Lysine) and Lysine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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