Macrobid and Device failure - a phase IV clinical study of FDA data

Summary:

Device failure is reported as a side effect among people who take Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline), especially for people who are female, 20-29 old, also take Mirena, and have Birth control.

The phase IV clinical study analyzes which people have Device failure when taking Macrobid. It is created by eHealthMe based on reports of 8,335 people who have side effects when taking Macrobid from the FDA, and is updated regularly.

What is Macrobid?

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 9,215 Macrobid users. Check the latest studies of Macrobid.

What is Device failure?

Device failure is found to be associated with 751 drugs and 761 conditions by eHealthMe. Check the latest studies of Device failure.

On Jul, 17, 2026

8,335 people reported to have side effects when taking Macrobid.
Among them, 19 people (0.23%) have Device failure.

Among these 19 people:

What is the gender of people who have Device failure when taking Macrobid? *

female: 89.47 %
male: 10.53 %

What is the age of people who have Device failure when taking Macrobid? *

What are other drugs people take besides Macrobid? *

What are other side effects people have besides Device failure? *

Injury: 7 people, 36.84%
Emotional Distress: 6 people, 31.58%
Uterine Perforation (accidental puncture of the uterus): 5 people, 26.32%
Bone Disorder: 5 people, 26.32%
Scar: 4 people, 21.05%
Drug Ineffective: 4 people, 21.05%
Pain: 4 people, 21.05%
Infection: 4 people, 21.05%
Swelling Face: 3 people, 15.79%
Therapeutic Response Decreased (less preventive response): 3 people, 15.79%

What are the existing conditions these people have? *

Birth Control: 6 people, 31.58%
Osteoporosis (bones weak and more likely to break): 5 people, 26.32%
Pain: 2 people, 10.53%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 10.53%
Multiple Allergies (allergy to multiple agents): 2 people, 10.53%
Heavy Or Prolong Menstrual Bleeding: 2 people, 10.53%
Upper Respiratory Tract Infection: 1 person, 5.26%
Type 2 Diabetes: 1 person, 5.26%
Quadriplegia (a four limb paralysis): 1 person, 5.26%
Procedural Pain: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Macrobid and have Device failure?

- Check whether Device failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Macrobid:

Macrobid (9,215 reports)

Device failure treatments and more:

Device failure (17,275 reports)

How severe was Device failure and when was it recovered:

Device failure in Macrobid

Expand to all the drugs that have ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline:

Device failure and drugs with ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Macrobid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Device failure:

Device failure (751 drugs)

Browse all the conditions that are associated with Device failure:

Device failure (761 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin; nitrofurantoin, macrocrystalline (the active ingredients of Macrobid) and Macrobid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.