Macrobid and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Macrobid. It is created by eHealthMe based on reports of 8,335 people who have side effects when taking Macrobid from the FDA, and is updated regularly.

What is Macrobid?

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 9,214 Macrobid users. Check the latest studies of Macrobid.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,706 drugs and 1,582 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Sep, 11, 2025

8,335 people reported to have side effects when taking Macrobid.
Among them, 37 people (0.44%) have Thyroid function test abnormal.

Could Macrobid cause Thyroid function test abnormal?

Among these 37 people:

How long have people been on Macrobid when they have Thyroid function test abnormal? *

What is the gender of people who have Thyroid function test abnormal when taking Macrobid? *

female: 100 %
male: 0.0 %

What is the age of people who have Thyroid function test abnormal when taking Macrobid? *

What are other drugs people take besides Macrobid? *

What are other side effects people have besides Thyroid function test abnormal? *

Fatigue (feeling of tiredness): 25 people, 67.57%
Pain: 21 people, 56.76%
Weight Decreased: 21 people, 56.76%
Dyspnea (difficult or laboured breathing): 20 people, 54.05%
Rashes (redness): 20 people, 54.05%
Constipation: 20 people, 54.05%
Heart Rate Increased: 19 people, 51.35%
Peripheral Swelling: 18 people, 48.65%
Abdominal Distension: 18 people, 48.65%
Muscle Spasms (muscle contraction): 17 people, 45.95%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 18 people, 48.65%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 10.81%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 8.11%
Ovarian Epithelial Cancer (cancer that begins in the cells on the surface of the ovary): 3 people, 8.11%
Arthritis Enteropathic (form of chronic, inflammatory arthritis associated with the occurrence of an inflammatory bowel disease): 3 people, 8.11%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 8.11%
Insomnia (sleeplessness): 3 people, 8.11%
Ovarian Cancer (cancer of ovary): 3 people, 8.11%
Ovarian Cancer Stage Iii: 3 people, 8.11%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

Do you take Macrobid and have Thyroid function test abnormal?

- Check whether Thyroid function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Macrobid:

Macrobid (9,214 reports)

Thyroid function test abnormal treatments and more:

Thyroid function test abnormal (69,453 reports)

How severe was Thyroid function test abnormal and when was it recovered:

Thyroid function test abnormal in Macrobid

Expand to all the drugs that have ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline:

Thyroid function test abnormal and drugs with ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Macrobid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,706 drugs)

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,582 conditions)

Drugs similar to Macrobid and Thyroid function test abnormal :

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin; nitrofurantoin, macrocrystalline (the active ingredients of Macrobid) and Macrobid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.