Macrobid and Uc - a phase IV clinical study of FDA data

Summary:

Uc is reported as a side effect among people who take Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Cymbalta, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Uc when taking Macrobid. It is created by eHealthMe based on reports of 8,335 people who have side effects when taking Macrobid from the FDA, and is updated regularly.

What is Macrobid?

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 9,215 Macrobid users. Check the latest studies of Macrobid.

What is Uc?

Uc is found to be associated with 1,308 drugs and 2,020 conditions by eHealthMe. Check the latest studies of Uc.

On Oct, 02, 2025

8,335 people reported to have side effects when taking Macrobid.
Among them, 17 people (0.2%) have Uc.

Among these 17 people:

How long have people been on Macrobid when they have Uc? *

What is the gender of people who have Uc when taking Macrobid? *

female: 82.35 %
male: 17.65 %

What is the age of people who have Uc when taking Macrobid? *

What are other drugs people take besides Macrobid? *

What are other side effects people have besides Uc? *

Weakness: 6 people, 35.29%
Speech Impairment (Adult) (inability to speak (adult)): 5 people, 29.41%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 5 people, 29.41%
Wound: 4 people, 23.53%
Road Traffic Accident: 4 people, 23.53%
Confusion: 4 people, 23.53%
Pneumonia: 4 people, 23.53%
Pain: 4 people, 23.53%
Costochondritis (chest wall pain): 4 people, 23.53%
Cough: 4 people, 23.53%

What are the existing conditions these people have? *

Depression: 5 people, 29.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 29.41%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 23.53%
Oedema Peripheral (superficial swelling): 4 people, 23.53%
Acne (skin problems that cause pimples): 2 people, 11.76%
Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 5.88%
Impaired Gastric Emptying: 1 person, 5.88%
Diarrhea: 1 person, 5.88%
Diarrhea Haemorrhagic: 1 person, 5.88%
Headache (pain in head): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Macrobid and have Uc?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Macrobid:

Macrobid (9,215 reports)

Uc treatments and more:

Uc (188,231 reports)

How severe was Uc and when was it recovered:

Uc in Macrobid

Expand to all the drugs that have ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline:

Uc and drugs with ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline (25 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Macrobid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Uc:

Uc (1,308 drugs)

Browse all the conditions that are associated with Uc:

Uc (2,020 conditions)

Drugs similar to Macrobid and Uc :

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin; nitrofurantoin, macrocrystalline (the active ingredients of Macrobid) and Macrobid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.