Macrodantin and Dry skin - a phase IV clinical study of FDA data

Summary:

Dry skin is reported as a side effect among people who take Macrodantin (nitrofurantoin, macrocrystalline), especially for people who are female, 60+ old, also take Vitamin D3, and have Bladder disorder.

The phase IV clinical study analyzes which people have Dry skin when taking Macrodantin. It is created by eHealthMe based on reports of 3,567 people who have side effects when taking Macrodantin from the FDA, and is updated regularly.

What is Macrodantin?

Macrodantin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 3,755 Macrodantin users. Check the latest studies of Macrodantin.

What is Dry skin?

Dry skin is found to be associated with 1,977 drugs and 2,356 conditions by eHealthMe. Check the latest studies of Dry skin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

3,567 people reported to have side effects when taking Macrodantin.
Among them, 17 people (0.48%) have Dry skin.

Among these 17 people:

What is the gender of people who have Dry skin when taking Macrodantin? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Dry skin when taking Macrodantin? *

What are other drugs people take besides Macrodantin? *

What are other side effects people have besides Dry skin? *

Asthma: 10 people, 58.82%
Weakness: 9 people, 52.94%
Fatigue (feeling of tiredness): 9 people, 52.94%
Back Pain: 8 people, 47.06%
Stomatitis (inflammation of mucous membrane of mouth): 8 people, 47.06%
Hoarseness Or Changing Voice: 8 people, 47.06%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 8 people, 47.06%
Rashes (redness): 8 people, 47.06%
Ear Pain: 8 people, 47.06%
Muscle Spasms (muscle contraction): 8 people, 47.06%

What are the existing conditions these people have? *

Urethritis Noninfective (inflammation of the urethra - non infective): 7 people, 41.18%
Pain: 7 people, 41.18%
Blood Glucose Abnormal: 7 people, 41.18%
Cough: 7 people, 41.18%
Gait Disturbance: 7 people, 41.18%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 41.18%
Bladder Disorder: 7 people, 41.18%
Itching: 5 people, 29.41%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 23.53%
Diarrhea: 3 people, 17.65%

* Approximation only. Some reports may have incomplete information.

Do you take Macrodantin and have Dry skin?

- Check whether Dry skin is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Macrodantin:

Macrodantin (3,755 reports)

Dry skin treatments and more:

Dry skin (131,311 reports)

How severe was Dry skin and when was it recovered:

Dry skin in Macrodantin

Expand to all the drugs that have ingredients of nitrofurantoin, macrocrystalline:

Dry skin and drugs with ingredients of nitrofurantoin, macrocrystalline (13 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Macrodantin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dry skin:

Dry skin (1,977 drugs)

Browse all the conditions that are associated with Dry skin:

Dry skin (2,356 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin, macrocrystalline (the active ingredients of Macrodantin) and Macrodantin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.