Marcaine and Muscle spasms - a phase IV clinical study of FDA data

Summary:

Muscle spasms is reported as a side effect among people who take Marcaine (bupivacaine hydrochloride), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Dilaudid, and have High blood pressure.

The phase IV clinical study analyzes which people have Muscle spasms when taking Marcaine. It is created by eHealthMe based on reports of 3,971 people who have side effects when taking Marcaine from the FDA, and is updated regularly.

What is Marcaine?

Marcaine has active ingredients of bupivacaine hydrochloride. It is often used in pain. eHealthMe is studying from 4,026 Marcaine users. Check the latest studies of Marcaine.

What is Muscle spasms?

Muscle spasms (muscle contraction) is found to be associated with 2,670 drugs and 3,100 conditions by eHealthMe. Check the latest studies of Muscle spasms.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 27, 2026

3,971 people reported to have side effects when taking Marcaine.
Among them, 45 people (1.13%) have Muscle spasms.

Among these 45 people:

How long have people been on Marcaine when they have Muscle spasms? *

What is the gender of people who have Muscle spasms when taking Marcaine? *

female: 40.91 %
male: 59.09 %

What is the age of people who have Muscle spasms when taking Marcaine? *

What are other drugs people take besides Marcaine? *

What are other side effects people have besides Muscle spasms? *

Headache (pain in head): 22 people, 48.89%
Stress And Anxiety: 21 people, 46.67%
Constipation: 20 people, 44.44%
Fatigue (feeling of tiredness): 18 people, 40.00%
Dizziness: 17 people, 37.78%
Joint Pain: 17 people, 37.78%
Disturbance In Attention: 16 people, 35.56%
Tremor (trembling or shaking movements in one or more parts of your body): 15 people, 33.33%
Depression: 15 people, 33.33%
Nausea (feeling of having an urge to vomit): 15 people, 33.33%

What are the existing conditions these people have? *

Thrombosis (formation of a blood clot inside a blood vessel): 7 people, 15.56%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 15.56%
High Blood Pressure: 7 people, 15.56%
Constipation: 6 people, 13.33%
Hypersensitivity: 6 people, 13.33%
Ill-Defined Disorder: 6 people, 13.33%
Stress And Anxiety: 6 people, 13.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 11.11%
Anaesthesia: 3 people, 6.67%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Marcaine and have Muscle spasms?

- Check whether Muscle spasms is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Marcaine:

Marcaine (4,026 reports)

Muscle spasms treatments and more:

Muscle spasms (238,419 reports)

Browse all side effects of Marcaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle spasms:

Muscle spasms (2,670 drugs)

Browse all the conditions that are associated with Muscle spasms:

Muscle spasms (3,100 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bupivacaine hydrochloride (the active ingredients of Marcaine) and Marcaine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.