Maxalt and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Maxalt (rizatriptan benzoate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cymbalta, and have Multiple sclerosis.

The study is created by eHealthMe based on reports of 11,566 people who have side effects when taking Maxalt from the FDA, and is updated regularly.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,753 Maxalt users. Check the latest studies of Maxalt.

On Apr, 20, 2026

11,566 people reported to have side effects when taking Maxalt.
Among them, 92 people (0.8%) died.

Among these 92 people:

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Maxalt:

Maxalt (12,753 reports)

Expand to all the drugs that have ingredients of rizatriptan benzoate:

Death and drugs with ingredients of rizatriptan benzoate (140 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,159 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rizatriptan benzoate (the active ingredients of Maxalt) and Maxalt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Maxalt and Death - a phase IV clinical study of FDA data

Summary:

What is Maxalt?

Among these 92 people:

How long have people been on Maxalt when they died? *

What is the gender of people who died when taking Maxalt? *

What is the age of people who died when taking Maxalt? *

What are other drugs people take besides Maxalt? *

What are other side effects people have before they died? *

What are the existing conditions these people have? *