Maxalt and Icterus - a phase IV clinical study of FDA data

Summary:

Icterus is reported as a side effect among people who take Maxalt (rizatriptan benzoate), especially for people who are female, 30-39 old, also take Topamax, and have Birth control.

The phase IV clinical study analyzes which people have Icterus when taking Maxalt. It is created by eHealthMe based on reports of 11,566 people who have side effects when taking Maxalt from the FDA, and is updated regularly.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,752 Maxalt users. Check the latest studies of Maxalt.

What is Icterus?

Icterus (yellowish pigmentation of the skin) is found to be associated with 2,211 drugs and 2,985 conditions by eHealthMe. Check the latest studies of Icterus.



On Oct, 16, 2025

11,566 people reported to have side effects when taking Maxalt.
Among them, 16 people (0.14%) have Icterus.

Could Maxalt cause Icterus?

Among these 16 people:

What is the gender of people who have Icterus when taking Maxalt? *

  • female: 93.75 %
  • male: 6.25 %

What is the age of people who have Icterus when taking Maxalt? *

  • 0-1: 21.43 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 64.29 %
  • 40-49: 7.14 %
  • 50-59: 7.14 %
  • 60+: 0.0 %

What are other drugs people take besides Maxalt? *

  1. Drospirenone And Ethinyl Estradiol: 5 people, 31.25%
  2. Tylenol: 5 people, 31.25%
  3. Topamax: 5 people, 31.25%
  4. Naproxen: 4 people, 25.00%
  5. Fioricet: 4 people, 25.00%
  6. Nuvaring: 4 people, 25.00%
  7. Vicodin: 3 people, 18.75%
  8. Valium: 3 people, 18.75%
  9. Unisom: 3 people, 18.75%
  10. Tylenol W/ Codeine No. 3: 3 people, 18.75%

What are other side effects people have besides Icterus? *

  1. Nausea (feeling of having an urge to vomit): 7 people, 43.75%
  2. Chest Pain: 5 people, 31.25%
  3. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 5 people, 31.25%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
  5. Post-Traumatic Pain: 4 people, 25.00%
  6. Laryngitis (inflammation of the larynx): 4 people, 25.00%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 25.00%
  8. Intervertebral Disc Protrusion (spinal disc protrusion): 4 people, 25.00%
  9. Intervertebral Disc Degeneration (spinal disc degeneration): 4 people, 25.00%
  10. Dyspnea (difficult or laboured breathing): 4 people, 25.00%

What are the existing conditions these people have? *

  1. Birth Control: 4 people, 25.00%
  2. Back Pain: 3 people, 18.75%
  3. Asthma: 3 people, 18.75%
  4. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 1 person, 6.25%
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 6.25%
  6. Alcoholism (problems with alcohol): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Maxalt and have Icterus?

- Check whether Icterus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Maxalt:

Icterus treatments and more:

How severe was Icterus and when was it recovered:

Expand to all the drugs that have ingredients of rizatriptan benzoate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Icterus:

Browse all the conditions that are associated with Icterus:

Drugs similar to Maxalt and Icterus :


How the study uses the data?

The study uses data from the FDA. It is based on rizatriptan benzoate (the active ingredients of Maxalt) and Maxalt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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