Maxzide and Atherosclerosis - a phase IV clinical study of FDA data

Summary:

Atherosclerosis is reported as a side effect among people who take Maxzide (hydrochlorothiazide; triamterene), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Aspirin, and have Pain.

The phase IV clinical study analyzes which people have Atherosclerosis when taking Maxzide. It is created by eHealthMe based on reports of 8,853 people who have side effects when taking Maxzide from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Atherosclerosis?

Atherosclerosis (disorder of the arteries) is found to be associated with 1,214 drugs and 1,529 conditions by eHealthMe. Check the latest studies of Atherosclerosis.

On Jul, 08, 2026

8,853 people reported to have side effects when taking Maxzide.
Among them, 50 people (0.56%) have Atherosclerosis.

Among these 50 people:

How long have people been on Maxzide when they have Atherosclerosis? *

What is the gender of people who have Atherosclerosis when taking Maxzide? *

female: 72 %
male: 28 %

What is the age of people who have Atherosclerosis when taking Maxzide? *

What are other drugs people take besides Maxzide? *

What are other side effects people have besides Atherosclerosis? *

Pain: 23 people, 46.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 18 people, 36.00%
Joint Pain: 17 people, 34.00%
Stress And Anxiety: 17 people, 34.00%
Cataract (clouding of the lens inside the eye): 17 people, 34.00%
Osteonecrosis Of Jaw (death of bone of jaw): 16 people, 32.00%
Death: 16 people, 32.00%
Enlarged Heart: 16 people, 32.00%
Bone Disorder: 16 people, 32.00%
Neuropathy Peripheral (surface nerve damage): 16 people, 32.00%

What are the existing conditions these people have? *

Gout (uric acid crystals building up in the body): 8 people, 16.00%
Stress And Anxiety: 8 people, 16.00%
Bone Loss: 8 people, 16.00%
Pain: 8 people, 16.00%
Metastases To Bone (cancer spreads to bone): 7 people, 14.00%
Bone Pain: 7 people, 14.00%
Bone Disorder: 7 people, 14.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 14.00%
Anaemia (lack of blood): 7 people, 14.00%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 7 people, 14.00%

* Approximation only. Some reports may have incomplete information.

Do you take Maxzide and have Atherosclerosis?

- Check whether Atherosclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Maxzide:

Maxzide (9,152 reports)

Atherosclerosis treatments and more:

Atherosclerosis (21,888 reports)

How severe was Atherosclerosis and when was it recovered:

Atherosclerosis in Maxzide

Expand to all the drugs that have ingredients of hydrochlorothiazide; triamterene:

Atherosclerosis and drugs with ingredients of hydrochlorothiazide; triamterene (165 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxzide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atherosclerosis:

Atherosclerosis (1,214 drugs)

Browse all the conditions that are associated with Atherosclerosis:

Atherosclerosis (1,529 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; triamterene (the active ingredients of Maxzide) and Maxzide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.