Maxzide and Impaired driving ability - a phase IV clinical study of FDA data

Summary:

Impaired driving ability is reported as a side effect among people who take Maxzide (hydrochlorothiazide; triamterene), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Avapro, and have Blood pressure abnormal.

The phase IV clinical study analyzes which people have Impaired driving ability when taking Maxzide. It is created by eHealthMe based on reports of 8,853 people who have side effects when taking Maxzide from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Impaired driving ability?

Impaired driving ability is found to be associated with 738 drugs and 932 conditions by eHealthMe. Check the latest studies of Impaired driving ability.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

8,853 people reported to have side effects when taking Maxzide.
Among them, 14 people (0.16%) have Impaired driving ability.

Could Maxzide cause Impaired driving ability?

Among these 14 people:

How long have people been on Maxzide when they have Impaired driving ability? *

What is the gender of people who have Impaired driving ability when taking Maxzide? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Impaired driving ability when taking Maxzide? *

What are other drugs people take besides Maxzide? *

What are other side effects people have besides Impaired driving ability? *

Dizziness: 8 people, 57.14%
Drug Ineffective: 6 people, 42.86%
Headache (pain in head): 6 people, 42.86%
Weakness: 5 people, 35.71%
Speech Disorder: 5 people, 35.71%
Dyskinesia (abnormality or impairment of voluntary movement): 4 people, 28.57%
Depression: 3 people, 21.43%
Oedema Peripheral (superficial swelling): 3 people, 21.43%
Fatigue (feeling of tiredness): 3 people, 21.43%
Fall: 3 people, 21.43%

What are the existing conditions these people have? *

Blood Pressure Abnormal: 2 people, 14.29%
Stress And Anxiety: 1 person, 7.14%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.14%
Affective Disorder (mental disorder): 1 person, 7.14%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.14%
Depression: 1 person, 7.14%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
Headache (pain in head): 1 person, 7.14%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Maxzide and have Impaired driving ability?

- Check whether Impaired driving ability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Maxzide:

Maxzide (9,152 reports)

Impaired driving ability treatments and more:

Impaired driving ability (12,655 reports)

How severe was Impaired driving ability and when was it recovered:

Impaired driving ability in Maxzide

Expand to all the drugs that have ingredients of hydrochlorothiazide; triamterene:

Impaired driving ability and drugs with ingredients of hydrochlorothiazide; triamterene (57 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxzide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Impaired driving ability:

Impaired driving ability (738 drugs)

Browse all the conditions that are associated with Impaired driving ability:

Impaired driving ability (932 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; triamterene (the active ingredients of Maxzide) and Maxzide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.