Maxzide and Toothaches - a phase IV clinical study of FDA data

Summary:

Toothaches is reported as a side effect among people who take Maxzide (hydrochlorothiazide; triamterene), especially for people who are male, 60+ old, also take Norvasc, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Toothaches when taking Maxzide. It is created by eHealthMe based on reports of 8,853 people who have side effects when taking Maxzide from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Toothaches?

Toothaches (tooth pain) is found to be associated with 1,320 drugs and 1,606 conditions by eHealthMe. Check the latest studies of Toothaches.

On Aug, 11, 2026

8,853 people reported to have side effects when taking Maxzide.
Among them, 32 people (0.36%) have Toothaches.

Among these 32 people:

What is the gender of people who have Toothaches when taking Maxzide? *

female: 46.67 %
male: 53.33 %

What is the age of people who have Toothaches when taking Maxzide? *

What are other drugs people take besides Maxzide? *

What are other side effects people have besides Toothaches? *

Osteomyelitis (infection of bone): 23 people, 71.88%
Constipation: 21 people, 65.62%
Rashes (redness): 21 people, 65.62%
Weight Decreased: 17 people, 53.12%
Weakness: 17 people, 53.12%
Pain: 17 people, 53.12%
Discomfort: 16 people, 50.00%
Excessive Granulation Tissue (excessive collagen-rich tissue which forms at the site of an injury): 16 people, 50.00%
Fall: 16 people, 50.00%
Purulent Discharge (discharge that contains pus): 16 people, 50.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 16 people, 50.00%
Osteoporosis (bones weak and more likely to break): 8 people, 25.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 21.88%
Bone Marrow Oedema Syndrome (transient clinical conditions -the disease mainly affects the hip, the knee, and the ankle of middle-aged males): 6 people, 18.75%
Insomnia (sleeplessness): 3 people, 9.38%
Joint Pain: 2 people, 6.25%
Type 2 Diabetes: 1 person, 3.12%
Sneezing: 1 person, 3.12%
Pain: 1 person, 3.12%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Maxzide and have Toothaches?

- Check whether Toothaches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Maxzide:

Maxzide (9,152 reports)

Toothaches treatments and more:

Toothaches (28,231 reports)

How severe was Toothaches and when was it recovered:

Toothaches in Maxzide

Expand to all the drugs that have ingredients of hydrochlorothiazide; triamterene:

Toothaches and drugs with ingredients of hydrochlorothiazide; triamterene (161 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxzide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Toothaches:

Toothaches (1,320 drugs)

Browse all the conditions that are associated with Toothaches:

Toothaches (1,606 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; triamterene (the active ingredients of Maxzide) and Maxzide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.