Mayzent and Hot flushes aggravated - a phase IV clinical study of FDA data

Summary:

Hot flushes aggravated is reported as a side effect among people who take Mayzent (siponimod fumaric acid), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Fish Oil, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Hot flushes aggravated when taking Mayzent. It is created by eHealthMe based on reports of 10,267 people who have side effects when taking Mayzent from the FDA, and is updated regularly.

What is Mayzent?

Mayzent has active ingredients of siponimod fumaric acid. eHealthMe is studying from 10,269 Mayzent users. Check the latest studies of Mayzent.

What is Hot flushes aggravated?

Hot flushes aggravated (sudden feelings of heat) is found to be associated with 1,518 drugs and 475 conditions by eHealthMe. Check the latest studies of Hot flushes aggravated.

On Jul, 12, 2026

10,267 people reported to have side effects when taking Mayzent.
Among them, 43 people (0.42%) have Hot flushes aggravated.

Could Mayzent cause Hot flushes aggravated?

Among these 43 people:

How long have people been on Mayzent when they have Hot flushes aggravated? *

What is the gender of people who have Hot flushes aggravated when taking Mayzent? *

female: 95 %
male: 5 %

What is the age of people who have Hot flushes aggravated when taking Mayzent? *

What are other drugs people take besides Mayzent? *

What are other side effects people have besides Hot flushes aggravated? *

Headache (pain in head): 14 people, 32.56%
Fatigue (feeling of tiredness): 13 people, 30.23%
Weakness: 8 people, 18.60%
Memory Loss: 7 people, 16.28%
Rashes (redness): 5 people, 11.63%
Gait Disturbance: 5 people, 11.63%
Dyspnea (difficult or laboured breathing): 4 people, 9.30%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 4 people, 9.30%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 9.30%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 9.30%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 26 people, 60.47%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 6 people, 13.95%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 9.30%
Muscle Spasms (muscle contraction): 2 people, 4.65%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Mayzent and have Hot flushes aggravated?

- Check whether Hot flushes aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mayzent:

Mayzent (10,269 reports)

Browse all side effects of Mayzent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flushes aggravated:

Hot flushes aggravated (1,518 drugs)

Browse all the conditions that are associated with Hot flushes aggravated:

Hot flushes aggravated (475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on siponimod fumaric acid (the active ingredients of Mayzent) and Mayzent (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.