Meclizine and Hypothyroidism - a phase IV clinical study of FDA data


Hypothyroidism is found among people who take Meclizine, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Meclizine and have Hypothyroidism. It is created by eHealthMe based on reports of 19,556 people who have side effects when taking Meclizine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 25, 2022

19,556 people reported to have side effects when taking Meclizine.
Among them, 85 people (0.43%) have Hypothyroidism.

What is Meclizine?

Meclizine has active ingredients of meclizine hydrochloride. It is often used in dizziness. eHealthMe is studying from 20,359 Meclizine users for its effectiveness, alternative drugs and more.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 2,804 drugs and 2,372 conditions by eHealthMe.

Number of Meclizine and Hypothyroidism reports submitted per year:

Could Meclizine cause Hypothyroidism?

Time on Meclizine when people have Hypothyroidism *:

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Hypothyroidism when taking Meclizine *:

  • female: 98.8 %
  • male: 1.2 %

Age of people who have Hypothyroidism when taking Meclizine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 4.48 %
  • 30-39: 4.48 %
  • 40-49: 25.37 %
  • 50-59: 23.88 %
  • 60+: 41.79 %

Common drugs people take besides Meclizine *:

  1. Aspirin: 27 people, 31.76%
  2. Nexium: 26 people, 30.59%
  3. Synthroid: 20 people, 23.53%
  4. Xanax: 20 people, 23.53%
  5. Diazepam: 19 people, 22.35%
  6. Crestor: 19 people, 22.35%
  7. Celexa: 19 people, 22.35%
  8. Levothyroxine Sodium: 19 people, 22.35%
  9. Lipitor: 18 people, 21.18%
  10. Neurontin: 18 people, 21.18%

Common side effects people have besides Hypothyroidism *:

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 35 people, 41.18%
  2. Depression: 35 people, 41.18%
  3. Stress And Anxiety: 35 people, 41.18%
  4. Pain: 33 people, 38.82%
  5. High Blood Pressure: 28 people, 32.94%
  6. Breathing Difficulty: 25 people, 29.41%
  7. Diabetes: 24 people, 28.24%
  8. Anaemia (lack of blood): 23 people, 27.06%
  9. Joint Pain: 23 people, 27.06%
  10. Fall: 23 people, 27.06%

Common conditions people have *:

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 15.29%
  2. Cardiac Disorder: 12 people, 14.12%
  3. Quit Smoking: 11 people, 12.94%
  4. Breast Cancer: 11 people, 12.94%
  5. Bone Neoplasm Malignant (cancer of bone): 10 people, 11.76%
  6. Pain: 10 people, 11.76%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 10.59%
  8. Hypersensitivity: 8 people, 9.41%
  9. Wheezing (a high-pitched whistling sound made while you breath): 8 people, 9.41%
  10. Bone Loss: 7 people, 8.24%

* Approximation only. Some reports may have incomplete information.

Do you take Meclizine and have Hypothyroidism?

Check whether Hypothyroidism is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Hypothyroidism and when was it recovered:

Expand to all the drugs that have ingredients of meclizine hydrochloride:

Alternative drugs to, pros and cons of Meclizine:

Common Meclizine side effects:

Browse all side effects of Meclizine:

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Hypothyroidism treatments and more:

COVID vaccines that are related to Hypothyroidism:

Common drugs associated with Hypothyroidism:

All the drugs that are associated with Hypothyroidism:

Common conditions associated with Hypothyroidism:

All the conditions that are associated with Hypothyroidism:

How the study uses the data?

The study uses data from the FDA. It is based on meclizine hydrochloride (the active ingredients of Meclizine) and Meclizine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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