Megace and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Megace (megestrol acetate), especially for people who are 60+ old, have been taking the drug for 6 - 12 months also take Zometa, and have Prostate cancer.

The phase IV clinical study analyzes which people have Hot flush when taking Megace. It is created by eHealthMe based on reports of 9,969 people who have side effects when taking Megace from the FDA, and is updated regularly.

What is Megace?

Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,768 drugs and 2,344 conditions by eHealthMe. Check the latest studies of Hot flush.

On Jul, 09, 2026

9,969 people reported to have side effects when taking Megace.
Among them, 95 people (0.95%) have Hot flush.

Among these 95 people:

How long have people been on Megace when they have Hot flush? *

What is the age of people who have Hot flush when taking Megace? *

What are other drugs people take besides Megace? *

What are other side effects people have besides Hot flush? *

Pain: 55 people, 57.89%
Stress And Anxiety: 52 people, 54.74%
Fatigue (feeling of tiredness): 52 people, 54.74%
Back Pain: 46 people, 48.42%
Dyspnea (difficult or laboured breathing): 44 people, 46.32%
Osteonecrosis Of Jaw (death of bone of jaw): 44 people, 46.32%
Bone Disorder: 43 people, 45.26%
Joint Pain: 42 people, 44.21%
Weakness: 42 people, 44.21%
Impaired Healing: 41 people, 43.16%

What are the existing conditions these people have? *

Prostate Cancer: 19 people, 20.00%
Breast Cancer Metastatic: 16 people, 16.84%
Metastases To Bone (cancer spreads to bone): 15 people, 15.79%
Pain: 13 people, 13.68%
Depression: 10 people, 10.53%
Hypoaesthesia (reduced sense of touch or sensation): 8 people, 8.42%
Weakness: 8 people, 8.42%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 7.37%
Prostate Cancer Metastatic: 5 people, 5.26%
Stress And Anxiety: 4 people, 4.21%

* Approximation only. Some reports may have incomplete information.

Do you take Megace and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Megace:

Megace (10,095 reports)

Hot flush treatments and more:

Hot flush (91,208 reports)

Browse all side effects of Megace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Hot flush (1,768 drugs)

Browse all the conditions that are associated with Hot flush:

Hot flush (2,344 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on megestrol acetate (the active ingredients of Megace) and Megace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.