Megestrol acetate and Osteosclerosis - a phase IV clinical study of FDA data

Summary:

Osteosclerosis is reported as a side effect among people who take Megestrol acetate (megestrol acetate), especially for people who are female, 50-59 old, also take Zometa, and have Breast cancer.

The phase IV clinical study analyzes which people have Osteosclerosis when taking Megestrol acetate. It is created by eHealthMe based on reports of 5,359 people who have side effects when taking Megestrol acetate from the FDA, and is updated regularly.

What is Megestrol acetate?

Megestrol acetate has active ingredients of megestrol acetate. It is often used in appetite - decreased. eHealthMe is studying from 5,427 Megestrol acetate users. Check the latest studies of Megestrol acetate.

What is Osteosclerosis?

Osteosclerosis (an elevation in bone density) is found to be associated with 636 drugs and 399 conditions by eHealthMe. Check the latest studies of Osteosclerosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

5,359 people reported to have side effects when taking Megestrol acetate.
Among them, 40 people (0.75%) have Osteosclerosis.

Could Megestrol acetate cause Osteosclerosis?

Among these 40 people:

What is the gender of people who have Osteosclerosis when taking Megestrol acetate? *

female: 52.78 %
male: 47.22 %

What is the age of people who have Osteosclerosis when taking Megestrol acetate? *

What are other drugs people take besides Megestrol acetate? *

What are other side effects people have besides Osteosclerosis? *

Tooth Disorder (tooth disease): 36 people, 90.00%
Impaired Healing: 35 people, 87.50%
Hypoaesthesia (reduced sense of touch or sensation): 31 people, 77.50%
Pain In Jaw: 30 people, 75.00%
Joint Pain: 29 people, 72.50%
Nausea (feeling of having an urge to vomit): 29 people, 72.50%
Periodontal Disease (disease that attacks the gum and bone and around the teeth): 28 people, 70.00%
Rib Fracture: 28 people, 70.00%
Nausea And Vomiting: 28 people, 70.00%
Intervertebral Disc Protrusion (spinal disc protrusion): 27 people, 67.50%

What are the existing conditions these people have? *

Breast Cancer: 21 people, 52.50%
Ovarian Cancer (cancer of ovary): 20 people, 50.00%
Neoplasm Malignant (cancer tumour): 20 people, 50.00%
Migraine (headache): 20 people, 50.00%
Breast Cancer Metastatic: 20 people, 50.00%
Discomfort: 20 people, 50.00%
Granulocyte Count Decreased: 19 people, 47.50%
Prostate Cancer Metastatic: 10 people, 25.00%
Multiple Myeloma (cancer of the plasma cells): 8 people, 20.00%
Pain: 8 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Megestrol acetate and have Osteosclerosis?

- Check whether Osteosclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Megestrol acetate:

Megestrol acetate (5,427 reports)

Osteosclerosis treatments and more:

Osteosclerosis (2,741 reports)

Browse all side effects of Megestrol acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteosclerosis:

Osteosclerosis (636 drugs)

Browse all the conditions that are associated with Osteosclerosis:

Osteosclerosis (399 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on megestrol acetate (the active ingredients of Megestrol acetate) and Megestrol acetate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.