Melatonin and Apathy - a phase IV clinical study of FDA data

Summary:

Apathy is reported as a side effect among people who take Melatonin (melatonin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin D3, and have Attention deficit hyperactivity disorder.

The phase IV clinical study analyzes which people have Apathy when taking Melatonin. It is created by eHealthMe based on reports of 53,570 people who have side effects when taking Melatonin from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Apathy?

Apathy is found to be associated with 801 drugs and 1,162 conditions by eHealthMe. Check the latest studies of Apathy.

On Jul, 10, 2026

53,570 people reported to have side effects when taking Melatonin.
Among them, 73 people (0.14%) have Apathy.

Among these 73 people:

How long have people been on Melatonin when they have Apathy? *

What is the gender of people who have Apathy when taking Melatonin? *

female: 60.29 %
male: 39.71 %

What is the age of people who have Apathy when taking Melatonin? *

What are other drugs people take besides Melatonin? *

What are other side effects people have besides Apathy? *

Fatigue (feeling of tiredness): 41 people, 56.16%
Weakness: 19 people, 26.03%
Stress And Anxiety: 17 people, 23.29%
Nausea (feeling of having an urge to vomit): 17 people, 23.29%
Feeling Abnormal: 17 people, 23.29%
Memory Loss: 16 people, 21.92%
Depression: 15 people, 20.55%
Joint Pain: 14 people, 19.18%
Headache (pain in head): 13 people, 17.81%
Drowsiness: 13 people, 17.81%

What are the existing conditions these people have? *

Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 11 people, 15.07%
Stress And Anxiety: 10 people, 13.70%
Parkinson's Disease: 8 people, 10.96%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 8.22%
Depression: 6 people, 8.22%
Pain: 5 people, 6.85%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 6.85%
Panic Disorder: 5 people, 6.85%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 4 people, 5.48%
Functional Gastrointestinal Disorder (functional problem in separate organs of gastrointestinal system): 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

Do you take Melatonin and have Apathy?

- Check whether Apathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Melatonin:

Melatonin (56,212 reports)

Apathy treatments and more:

Apathy (16,905 reports)

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Apathy:

Apathy (801 drugs)

Browse all the conditions that are associated with Apathy:

Apathy (1,162 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on melatonin (the active ingredients of Melatonin) and Melatonin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.