Melatonin and Escherichia infection - a phase IV clinical study of FDA data

Summary:

Escherichia infection is reported as a side effect among people who take Melatonin (melatonin), especially for people who are male, 60+ old, also take Ondansetron, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Escherichia infection when taking Melatonin. It is created by eHealthMe based on reports of 53,570 people who have side effects when taking Melatonin from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Escherichia infection?

Escherichia infection (bacterial infection by escherichia coli) is found to be associated with 895 drugs and 885 conditions by eHealthMe. Check the latest studies of Escherichia infection.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

53,570 people reported to have side effects when taking Melatonin.
Among them, 43 people (0.08%) have Escherichia infection.

Could Melatonin cause Escherichia infection?

Among these 43 people:

What is the gender of people who have Escherichia infection when taking Melatonin? *

female: 34.15 %
male: 65.85 %

What is the age of people who have Escherichia infection when taking Melatonin? *

What are other drugs people take besides Melatonin? *

What are other side effects people have besides Escherichia infection? *

Infection: 27 people, 62.79%
Nausea And Vomiting: 15 people, 34.88%
Enterococcus Test Positive: 13 people, 30.23%
Nausea (feeling of having an urge to vomit): 13 people, 30.23%
Febrile Neutropenia (fever with reduced white blood cells): 13 people, 30.23%
Dehydration (dryness resulting from the removal of water): 13 people, 30.23%
Weakness: 13 people, 30.23%
Hypoaesthesia (reduced sense of touch or sensation): 12 people, 27.91%
Peripheral Swelling: 12 people, 27.91%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 11 people, 25.58%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 13 people, 30.23%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 25.58%
High Blood Pressure: 6 people, 13.95%
Nausea (feeling of having an urge to vomit): 4 people, 9.30%
Depression: 4 people, 9.30%
Urinary Tract Infection: 3 people, 6.98%
Fungal Infection: 3 people, 6.98%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.98%
Glucocorticoids Abnormal: 2 people, 4.65%
Type 2 Diabetes: 2 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Melatonin and have Escherichia infection?

- Check whether Escherichia infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Melatonin:

Melatonin (56,212 reports)

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Escherichia infection:

Escherichia infection (895 drugs)

Browse all the conditions that are associated with Escherichia infection:

Escherichia infection (885 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on melatonin (the active ingredients of Melatonin) and Melatonin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.