Melatonin and Respiratory depression - a phase IV clinical study of FDA data

Summary:

Respiratory depression is reported as a side effect among people who take Melatonin (melatonin), especially for people who are male, 10-19 old, also take Pantoprazole, and have Pain.

The phase IV clinical study analyzes which people have Respiratory depression when taking Melatonin. It is created by eHealthMe based on reports of 53,570 people who have side effects when taking Melatonin from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Respiratory depression?

Respiratory depression (respiration has a rate below 12 breaths) is found to be associated with 716 drugs and 838 conditions by eHealthMe. Check the latest studies of Respiratory depression.

On Jul, 09, 2026

53,570 people reported to have side effects when taking Melatonin.
Among them, 237 people (0.44%) have Respiratory depression.

Could Melatonin cause Respiratory depression?

Among these 237 people:

What is the gender of people who have Respiratory depression when taking Melatonin? *

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What is the age of people who have Respiratory depression when taking Melatonin? *

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* Approximation only. Some reports may have incomplete information.

Do you take Melatonin and have Respiratory depression?

- Check whether Respiratory depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Melatonin:

Melatonin (56,212 reports)

Respiratory depression treatments and more:

Respiratory depression (14,450 reports)

How severe was Respiratory depression and when was it recovered:

Respiratory depression in Melatonin

Expand to all the drugs that have ingredients of melatonin:

Respiratory depression and drugs with ingredients of melatonin (237 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Respiratory depression:

Respiratory depression (716 drugs)

Browse all the conditions that are associated with Respiratory depression:

Respiratory depression (838 conditions)

Related publications that referenced our studies

Souki F, Shettar SS, "Prolonged respiratory depression after general anesthesia in an adult with congenital rubella syndrome", A&A Case Reports, 2013 Nov .
Souki F, Shettar SS, "Prolonged respiratory depression after general anesthesia in an adult with congenital rubella syndrome", A&A Case Reports, 2013 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on melatonin (the active ingredients of Melatonin) and Melatonin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.