Meloxicam and Breakthrough pain - a phase IV clinical study of FDA data

Summary:

Breakthrough pain is reported as a side effect among people who take Meloxicam (meloxicam), especially for people who are female, 60+ old, also take Xanax, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Breakthrough pain when taking Meloxicam. It is created by eHealthMe based on reports of 64,757 people who have side effects when taking Meloxicam from the FDA, and is updated regularly.

What is Meloxicam?

Meloxicam has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 68,016 Meloxicam users. Check the latest studies of Meloxicam.

What is Breakthrough pain?

Breakthrough pain is found to be associated with 271 drugs and 417 conditions by eHealthMe. Check the latest studies of Breakthrough pain.

On Jul, 05, 2026

64,757 people reported to have side effects when taking Meloxicam.
Among them, 15 people (0.02%) have Breakthrough pain.

Could Meloxicam cause Breakthrough pain?

Among these 15 people:

What is the gender of people who have Breakthrough pain when taking Meloxicam? *

female: 78.57 %
male: 21.43 %

What is the age of people who have Breakthrough pain when taking Meloxicam? *

What are other drugs people take besides Meloxicam? *

What are other side effects people have besides Breakthrough pain? *

Fatigue (feeling of tiredness): 3 people, 20.00%
Urinary Tract Infection: 2 people, 13.33%
Infection: 2 people, 13.33%
Back Pain: 2 people, 13.33%
Swelling: 2 people, 13.33%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 2 people, 13.33%
Nausea (feeling of having an urge to vomit): 2 people, 13.33%
Sinusitis (inflammation of sinus): 2 people, 13.33%
Drug Ineffective: 2 people, 13.33%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 2 people, 13.33%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 40.00%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 13.33%
Seasonal Allergy (allergic condition due to certain season): 2 people, 13.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%
Inflammation: 2 people, 13.33%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 6.67%
Atherosclerosis (disorder of the arteries): 1 person, 6.67%
Back Pain: 1 person, 6.67%
Depression: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Meloxicam and have Breakthrough pain?

- Check whether Breakthrough pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Meloxicam:

Meloxicam (68,016 reports)

Browse all side effects of Meloxicam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Breakthrough pain:

Breakthrough pain (271 drugs)

Browse all the conditions that are associated with Breakthrough pain:

Breakthrough pain (417 conditions)

Related publications that referenced our studies

Lai SW, Lin CL, Liao KF, "Association of Meloxicam Use with the Risk of Acute Pancreatitis: A Case–Control Study", Clinical drug investigation, 2015 Oct .
Lai SW, Lin CL, Liao KF, "Association of Meloxicam Use with the Risk of Acute Pancreatitis: A Case–Control Study", Clinical drug investigation, 2015 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on meloxicam (the active ingredients of Meloxicam) and Meloxicam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.