Melphalan hydrochloride and Liver disorder - a phase IV clinical study of FDA data

Summary:

Liver disorder is reported as a side effect among people who take Melphalan hydrochloride (melphalan hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Methotrexate, and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people have Liver disorder when taking Melphalan hydrochloride. It is created by eHealthMe based on reports of 3,963 people who have side effects when taking Melphalan hydrochloride from the FDA, and is updated regularly.

What is Melphalan hydrochloride?

Melphalan hydrochloride has active ingredients of melphalan hydrochloride. eHealthMe is studying from 3,970 Melphalan hydrochloride users. Check the latest studies of Melphalan hydrochloride.

What is Liver disorder?

Liver disorder (liver diseases) is found to be associated with 1,729 drugs and 2,042 conditions by eHealthMe. Check the latest studies of Liver disorder.

On Jul, 10, 2026

3,963 people reported to have side effects when taking Melphalan hydrochloride.
Among them, 33 people (0.83%) have Liver disorder.

Could Melphalan hydrochloride cause Liver disorder?

Among these 33 people:

How long have people been on Melphalan hydrochloride when they have Liver disorder? *

What is the gender of people who have Liver disorder when taking Melphalan hydrochloride? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Liver disorder when taking Melphalan hydrochloride? *

What are other drugs people take besides Melphalan hydrochloride? *

Methylprednisolone Sodium Succinate: 13 people, 39.39%
Tacrolimus: 13 people, 39.39%
Methotrexate: 13 people, 39.39%
Fludarabine Phosphate: 12 people, 36.36%
Dexamethasone: 11 people, 33.33%
Acyclovir: 10 people, 30.30%
Cyclophosphamide: 9 people, 27.27%
Itraconazole: 9 people, 27.27%
Prednisolone: 8 people, 24.24%
Mycophenolate Mofetil: 7 people, 21.21%

What are other side effects people have besides Liver disorder? *

Epstein-Barr Virus Infection: 13 people, 39.39%
Diarrhea: 11 people, 33.33%
Fever: 10 people, 30.30%
Cytomegalovirus Test Positive: 8 people, 24.24%
Febrile Neutropenia (fever with reduced white blood cells): 8 people, 24.24%
Thrombocytopenia (decrease of platelets in blood): 8 people, 24.24%
Acute Graft Versus Host Disease In Skin (acute complication on skin following an allogeneic tissue/blood transplant): 7 people, 21.21%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 6 people, 18.18%
Type 1 Diabetes: 6 people, 18.18%
Oxygen Saturation Decreased: 6 people, 18.18%

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 15 people, 45.45%
Multiple Myeloma (cancer of the plasma cells): 7 people, 21.21%
Aplastic Anemia: 6 people, 18.18%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 9.09%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 9.09%
Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 3 people, 9.09%
Cough: 2 people, 6.06%
Anaemia (lack of blood): 2 people, 6.06%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 6.06%
Insomnia (sleeplessness): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Melphalan hydrochloride and have Liver disorder?

- Check whether Liver disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Melphalan hydrochloride:

Melphalan hydrochloride (3,970 reports)

Liver disorder treatments and more:

Liver disorder (57,384 reports)

Browse all side effects of Melphalan hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver disorder:

Liver disorder (1,729 drugs)

Browse all the conditions that are associated with Liver disorder:

Liver disorder (2,042 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on melphalan hydrochloride (the active ingredients of Melphalan hydrochloride) and Melphalan hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.