Melphalan and Osteitis - a phase IV clinical study of FDA data

Summary:

Osteitis is reported as a side effect among people who take Melphalan (melphalan), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Osteitis when taking Melphalan. It is created by eHealthMe based on reports of 20,050 people who have side effects when taking Melphalan from the FDA, and is updated regularly.

What is Melphalan?

Melphalan has active ingredients of melphalan. eHealthMe is studying from 20,052 Melphalan users. Check the latest studies of Melphalan.

What is Osteitis?

Osteitis (a general term for inflammation of bone) is found to be associated with 620 drugs and 454 conditions by eHealthMe. Check the latest studies of Osteitis.



On Jul, 24, 2026

20,050 people reported to have side effects when taking Melphalan.
Among them, 14 people (0.07%) have Osteitis.

Could Melphalan cause Osteitis?

Among these 14 people:

How long have people been on Melphalan when they have Osteitis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Osteitis when taking Melphalan? *

  • female: 53.85 %
  • male: 46.15 %

What is the age of people who have Osteitis when taking Melphalan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 8.33 %
  • 50-59: 16.67 %
  • 60+: 75.0 %

What are other drugs people take besides Melphalan? *

  1. Zometa: 9 people, 64.29%
  2. Prednisone: 7 people, 50.00%
  3. Aredia: 6 people, 42.86%
  4. Thalidomide: 4 people, 28.57%
  5. Zoledronic Acid: 4 people, 28.57%
  6. Ativan: 3 people, 21.43%
  7. Hydrochlorothiazide: 3 people, 21.43%
  8. Colace: 3 people, 21.43%
  9. Miralax: 3 people, 21.43%
  10. Tylenol: 3 people, 21.43%

What are other side effects people have besides Osteitis? *

  1. Osteonecrosis Of Jaw (death of bone of jaw): 13 people, 92.86%
  2. Anaemia (lack of blood): 8 people, 57.14%
  3. Pain: 7 people, 50.00%
  4. Urinary Tract Infection: 7 people, 50.00%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 50.00%
  6. Stress And Anxiety: 7 people, 50.00%
  7. Joint Pain: 6 people, 42.86%
  8. Injury: 6 people, 42.86%
  9. Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 42.86%
  10. Atelectasis (partial or complete collapse of the lung): 6 people, 42.86%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 11 people, 78.57%
  2. Metastases To Bone (cancer spreads to bone): 4 people, 28.57%
  3. Pain: 2 people, 14.29%
  4. Immunodeficiency Disorders: 1 person, 7.14%
  5. Brain Neoplasm Malignant (brain cancer tumour): 1 person, 7.14%
  6. Colon Cancer: 1 person, 7.14%
  7. Depression: 1 person, 7.14%
  8. High Blood Pressure: 1 person, 7.14%
  9. Hypercalcaemia (elevated calcium (ca+) level in the blood): 1 person, 7.14%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Melphalan and have Osteitis?

- Check whether Osteitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Melphalan:

Osteitis treatments and more:

How severe was Osteitis and when was it recovered:

Expand to all the drugs that have ingredients of melphalan:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Melphalan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteitis:

Browse all the conditions that are associated with Osteitis:


How the study uses the data?

The study uses data from the FDA. It is based on melphalan (the active ingredients of Melphalan) and Melphalan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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