Melphalan and Renal injury - a phase IV clinical study of FDA data

Summary:

Renal injury is reported as a side effect among people who take Melphalan (melphalan), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Tacrolimus, and have High blood pressure.

The phase IV clinical study analyzes which people have Renal injury when taking Melphalan. It is created by eHealthMe based on reports of 20,050 people who have side effects when taking Melphalan from the FDA, and is updated regularly.

What is Melphalan?

Melphalan has active ingredients of melphalan. eHealthMe is studying from 20,052 Melphalan users. Check the latest studies of Melphalan.

What is Renal injury?

Renal injury (kidney injury) is found to be associated with 1,203 drugs and 794 conditions by eHealthMe. Check the latest studies of Renal injury.



On Aug, 09, 2026

20,050 people reported to have side effects when taking Melphalan.
Among them, 21 people (0.1%) have Renal injury.

Could Melphalan cause Renal injury?

Among these 21 people:

How long have people been on Melphalan when they have Renal injury? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Renal injury when taking Melphalan? *

  • female: 52.94 %
  • male: 47.06 %

What is the age of people who have Renal injury when taking Melphalan? *

  • 0-1: 0.0 %
  • 2-9: 18.75 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 6.25 %
  • 50-59: 18.75 %
  • 60+: 43.75 %

What are other drugs people take besides Melphalan? *

  1. Acyclovir: 5 people, 23.81%
  2. Tacrolimus: 5 people, 23.81%
  3. Vancomycin: 4 people, 19.05%
  4. Mycophenolate Mofetil: 4 people, 19.05%
  5. Thalidomide: 3 people, 14.29%
  6. Aredia: 3 people, 14.29%
  7. Cytarabine: 3 people, 14.29%
  8. Diflucan: 3 people, 14.29%
  9. Zometa: 3 people, 14.29%
  10. Valtrex: 3 people, 14.29%

What are other side effects people have besides Renal injury? *

  1. Rashes (redness): 7 people, 33.33%
  2. Fever: 6 people, 28.57%
  3. Hypotension (abnormally low blood pressure): 6 people, 28.57%
  4. Hepatic Failure (liver failure): 5 people, 23.81%
  5. Weakness: 5 people, 23.81%
  6. Mucosal Inflammation (infection of mucous membrane): 5 people, 23.81%
  7. Skin Exfoliation (removal of the oldest dead skin cells): 4 people, 19.05%
  8. Generalised Oedema (swelling all over the body): 4 people, 19.05%
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 4 people, 19.05%
  10. Circulatory Collapse: 4 people, 19.05%

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 19.05%
  2. Multiple Myeloma (cancer of the plasma cells): 4 people, 19.05%
  3. High Blood Pressure: 4 people, 19.05%
  4. Bone Marrow Conditioning Regimen: 3 people, 14.29%
  5. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 2 people, 9.52%
  6. Anaemia (lack of blood): 2 people, 9.52%
  7. Stable Angina (a constant chest pain): 2 people, 9.52%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.52%
  9. Diabetes: 1 person, 4.76%
  10. Breast Cancer: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Melphalan and have Renal injury?

- Check whether Renal injury is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Melphalan:

Renal injury treatments and more:

How severe was Renal injury and when was it recovered:

Expand to all the drugs that have ingredients of melphalan:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Melphalan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Renal injury:

Browse all the conditions that are associated with Renal injury:


How the study uses the data?

The study uses data from the FDA. It is based on melphalan (the active ingredients of Melphalan) and Melphalan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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