Mepron and Hepatic failure - a phase IV clinical study of FDA data

Summary:

Hepatic failure is reported as a side effect among people who take Mepron (atovaquone), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Phenergan, and have Hiv infection.

The phase IV clinical study analyzes which people have Hepatic failure when taking Mepron. It is created by eHealthMe based on reports of 2,035 people who have side effects when taking Mepron from the FDA, and is updated regularly.

What is Mepron?

Mepron has active ingredients of atovaquone. It is often used in babesiosis. eHealthMe is studying from 2,091 Mepron users. Check the latest studies of Mepron.

What is Hepatic failure?

Hepatic failure (liver failure) is found to be associated with 1,542 drugs and 1,891 conditions by eHealthMe. Check the latest studies of Hepatic failure.



On Jul, 06, 2026

2,035 people reported to have side effects when taking Mepron.
Among them, 16 people (0.79%) have Hepatic failure.

Could Mepron cause Hepatic failure?

Among these 16 people:

How long have people been on Mepron when they have Hepatic failure? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hepatic failure when taking Mepron? *

  • female: 18.75 %
  • male: 81.25 %

What is the age of people who have Hepatic failure when taking Mepron? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 15.38 %
  • 50-59: 76.92 %
  • 60+: 7.69 %

What are other drugs people take besides Mepron? *

  1. Selzentry: 6 people, 37.50%
  2. Benadryl: 6 people, 37.50%
  3. Diflucan: 6 people, 37.50%
  4. Truvada: 6 people, 37.50%
  5. Triamcinolone: 6 people, 37.50%
  6. Imodium: 6 people, 37.50%
  7. Isentress: 6 people, 37.50%
  8. Phenergan: 6 people, 37.50%
  9. Acyclovir: 4 people, 25.00%
  10. Acyclovir Sodium: 3 people, 18.75%

What are other side effects people have besides Hepatic failure? *

  1. Abdominal Pain: 6 people, 37.50%
  2. Aspartate Aminotransferase Increased: 6 people, 37.50%
  3. Cytomegalovirus Infection: 6 people, 37.50%
  4. Blood Bilirubin Increased: 6 people, 37.50%
  5. Diarrhea: 6 people, 37.50%
  6. Blood Amylase Increased: 6 people, 37.50%
  7. Eosinophil Count Increased: 6 people, 37.50%
  8. Fever: 6 people, 37.50%
  9. Blood Albumin Decreased: 6 people, 37.50%
  10. Bilirubin Conjugated Increased: 6 people, 37.50%

What are the existing conditions these people have? *

  1. Hiv Infection: 9 people, 56.25%
  2. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 12.50%
  3. High Blood Pressure: 2 people, 12.50%
  4. Neuropathy Peripheral (surface nerve damage): 2 people, 12.50%
  5. Depression: 2 people, 12.50%
  6. Diabetes: 2 people, 12.50%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 12.50%
  9. Osteoporosis (bones weak and more likely to break): 2 people, 12.50%
  10. Breathing Difficulty: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Mepron and have Hepatic failure?

- Check whether Hepatic failure is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mepron:

Hepatic failure treatments and more:

How severe was Hepatic failure and when was it recovered:

Expand to all the drugs that have ingredients of atovaquone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mepron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic failure:

Browse all the conditions that are associated with Hepatic failure:


How the study uses the data?

The study uses data from the FDA. It is based on atovaquone (the active ingredients of Mepron) and Mepron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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