Mesalamine and Lactic acidosis - a phase IV clinical study of FDA data

Summary:

Lactic acidosis is reported as a side effect among people who take Mesalamine (mesalamine), especially for people who are female, 50-59 old, also take Azathioprine, and have Antiphospholipid syndrome.

The phase IV clinical study analyzes which people have Lactic acidosis when taking Mesalamine. It is created by eHealthMe based on reports of 27,767 people who have side effects when taking Mesalamine from the FDA, and is updated regularly.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

What is Lactic acidosis?

Lactic acidosis (low ph in body tissues) is found to be associated with 995 drugs and 1,280 conditions by eHealthMe. Check the latest studies of Lactic acidosis.

On Aug, 04, 2026

27,767 people reported to have side effects when taking Mesalamine.
Among them, 11 people (0.04%) have Lactic acidosis.

Among these 11 people:

What is the gender of people who have Lactic acidosis when taking Mesalamine? *

female: 63.64 %
male: 36.36 %

What is the age of people who have Lactic acidosis when taking Mesalamine? *

What are other drugs people take besides Mesalamine? *

What are other side effects people have besides Lactic acidosis? *

Nocardia Infection (a bacterial infection that usually starts in the lungs. it may spread to other organ systems): 5 people, 45.45%
Adrenal Haemorrhage (bleeding into the adrenal gland): 5 people, 45.45%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 5 people, 45.45%
Cytomegalovirus Colitis (an inflammation of the colon from virus): 5 people, 45.45%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 45.45%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 5 people, 45.45%
Pulmonary Haemorrhage (acute bleeding from the lung): 5 people, 45.45%
Pneumonia: 3 people, 27.27%
Cellulitis (infection under the skin): 3 people, 27.27%
Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 3 people, 27.27%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%
Diabetes: 1 person, 9.09%
Cholangitis Sclerosing (infection and obstruction of bile duct): 1 person, 9.09%
Autoimmune Hepatitis: 1 person, 9.09%
Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Mesalamine and have Lactic acidosis?

- Check whether Lactic acidosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mesalamine:

Mesalamine (28,053 reports)

Lactic acidosis treatments and more:

Lactic acidosis (34,314 reports)

Browse all side effects of Mesalamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lactic acidosis:

Lactic acidosis (996 drugs)

Browse all the conditions that are associated with Lactic acidosis:

Lactic acidosis (1,280 conditions)

Related publications that referenced our studies

Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on mesalamine (the active ingredients of Mesalamine) and Mesalamine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.