Mesna and Anal inflammation - a phase IV clinical study of FDA data

Summary:

Anal inflammation is reported as a side effect among people who take Mesna (mesna), especially for people who are male, 20-29 old, have been taking the drug for 6 - 12 months also take Ifosfamide, and have Refractory cancer.

The phase IV clinical study analyzes which people have Anal inflammation when taking Mesna. It is created by eHealthMe based on reports of 9,641 people who have side effects when taking Mesna from the FDA, and is updated regularly.

What is Mesna?

Mesna has active ingredients of mesna. eHealthMe is studying from 9,647 Mesna users. Check the latest studies of Mesna.

What is Anal inflammation?

Anal inflammation is found to be associated with 136 drugs and 201 conditions by eHealthMe. Check the latest studies of Anal inflammation.

On Jul, 19, 2026

9,641 people reported to have side effects when taking Mesna.
Among them, 77 people (0.8%) have Anal inflammation.

Among these 77 people:

How long have people been on Mesna when they have Anal inflammation? *

What is the gender of people who have Anal inflammation when taking Mesna? *

female: 0.0 %
male: 100 %

What is the age of people who have Anal inflammation when taking Mesna? *

What are other drugs people take besides Mesna? *

Acetaminophen: 77 people, 100.00%
Cetirizine Hydrochloride: 77 people, 100.00%
Cyclophosphamide: 77 people, 100.00%
Ondansetron: 77 people, 100.00%
Ifosfamide: 77 people, 100.00%
Topotecan Hydrochloride: 76 people, 98.70%
Sulfamethoxazole: 73 people, 94.81%
Trimethoprim: 71 people, 92.21%
Morphine Sulfate: 71 people, 92.21%
Doxorubicin Hydrochloride: 70 people, 90.91%

What are other side effects people have besides Anal inflammation? *

Proctalgia (pain in the rectum): 77 people, 100.00%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 77 people, 100.00%
Febrile Neutropenia (fever with reduced white blood cells): 77 people, 100.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 77 people, 100.00%
Body Temperature Increased: 77 people, 100.00%
Back Pain: 77 people, 100.00%
Pain: 76 people, 98.70%
Malaise (a feeling of general discomfort or uneasiness): 76 people, 98.70%
Accident: 76 people, 98.70%
Nausea And Vomiting: 75 people, 97.40%

What are the existing conditions these people have? *

Tumor: 76 people, 98.70%
Refractory Cancer (cancer that has not responded to treatment): 76 people, 98.70%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 74 people, 96.10%
Adverse Event: 74 people, 96.10%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 66 people, 85.71%
Recurrent Cancer (repeated cancer): 64 people, 83.12%
Proctalgia (pain in the rectum): 62 people, 80.52%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 22 people, 28.57%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 2.60%
Body Temperature Increased: 2 people, 2.60%

* Approximation only. Some reports may have incomplete information.

Do you take Mesna and have Anal inflammation?

- Check whether Anal inflammation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mesna:

Mesna (9,647 reports)

Browse all side effects of Mesna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anal inflammation:

Anal inflammation (136 drugs)

Browse all the conditions that are associated with Anal inflammation:

Anal inflammation (201 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mesna (the active ingredients of Mesna) and Mesna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.