Mesna and Haematotoxicity - a phase IV clinical study of FDA data

Summary:

Haematotoxicity is reported as a side effect among people who take Mesna (mesna), especially for people who are female, 2-9 old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Ewing's sarcoma.

The phase IV clinical study analyzes which people have Haematotoxicity when taking Mesna. It is created by eHealthMe based on reports of 9,641 people who have side effects when taking Mesna from the FDA, and is updated regularly.

What is Mesna?

Mesna has active ingredients of mesna. eHealthMe is studying from 9,647 Mesna users. Check the latest studies of Mesna.

What is Haematotoxicity?

Haematotoxicity (toxins that destroy red blood cells) is found to be associated with 344 drugs and 829 conditions by eHealthMe. Check the latest studies of Haematotoxicity.

On Jul, 14, 2026

9,641 people reported to have side effects when taking Mesna.
Among them, 82 people (0.85%) have Haematotoxicity.

Among these 82 people:

How long have people been on Mesna when they have Haematotoxicity? *

What is the gender of people who have Haematotoxicity when taking Mesna? *

female: 54.76 %
male: 45.24 %

What is the age of people who have Haematotoxicity when taking Mesna? *

What are other drugs people take besides Mesna? *

Cyclophosphamide: 23 people, 28.05%
Etoposide: 22 people, 26.83%
Pentamidine Isethionate: 16 people, 19.51%
Carboplatin: 16 people, 19.51%
Thiotepa: 16 people, 19.51%
Melphalan Hydrochloride: 15 people, 18.29%
Fluconazole: 14 people, 17.07%
Ifosfamide: 14 people, 17.07%
Acyclovir: 10 people, 12.20%
Acyclovir Sodium: 6 people, 7.32%

What are other side effects people have besides Haematotoxicity? *

Mucosal Inflammation (infection of mucous membrane): 26 people, 31.71%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 21 people, 25.61%
Fever: 21 people, 25.61%
Sepsis (a severe blood infection that can lead to organ failure and death): 13 people, 15.85%
Drug Toxicity: 6 people, 7.32%
Death: 6 people, 7.32%
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 6 people, 7.32%
Febrile Neutropenia (fever with reduced white blood cells): 6 people, 7.32%
Gastrointestinal Toxicity (damage to digestive tract by any substance): 5 people, 6.10%
Infection: 5 people, 6.10%

What are the existing conditions these people have? *

Ewing's Sarcoma (malignant small, round, blue cell tumour): 22 people, 26.83%
Multiple Myeloma (cancer of the plasma cells): 10 people, 12.20%
Medulloblastoma (a fast-growing, high-grade tumour that always begins in the cerebellum): 9 people, 10.98%
Haematopoietic Stem Cell Mobilisation: 7 people, 8.54%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 6 people, 7.32%
Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 4 people, 4.88%
Angiocentric Lymphoma (extra nodal natural killer cell cancer): 4 people, 4.88%
Anaplastic Astrocytoma (tumour of the glial (supportive) tissue of the brain): 2 people, 2.44%
Pinealoblastoma (tumour of the pineal gland): 2 people, 2.44%
Breast Cancer: 2 people, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Mesna and have Haematotoxicity?

- Check whether Haematotoxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mesna:

Mesna (9,647 reports)

Haematotoxicity treatments and more:

Haematotoxicity (8,984 reports)

Browse all side effects of Mesna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haematotoxicity:

Haematotoxicity (344 drugs)

Browse all the conditions that are associated with Haematotoxicity:

Haematotoxicity (829 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mesna (the active ingredients of Mesna) and Mesna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.