Metadate cd and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Metadate cd (methylphenidate hydrochloride), especially for people who are female, 2-9 old, have been taking the drug for < 1 month also take Strattera, and have Narcolepsy.

The phase IV clinical study analyzes which people have Headache when taking Metadate cd. It is created by eHealthMe based on reports of 514 people who have side effects when taking Metadate cd from the FDA, and is updated regularly.

What is Metadate cd?

Metadate cd has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 646 Metadate cd users. Check the latest studies of Metadate cd.

What is Headache?

Headache (pain in head) is found to be associated with 3,747 drugs and 5,770 conditions by eHealthMe. Check the latest studies of Headache.

On Jul, 14, 2026

514 people reported to have side effects when taking Metadate cd.
Among them, 29 people (5.64%) have Headache.

Among these 29 people:

How long have people been on Metadate cd when they have Headache? *

What is the gender of people who have Headache when taking Metadate cd? *

female: 62.96 %
male: 37.04 %

What is the age of people who have Headache when taking Metadate cd? *

What are other drugs people take besides Metadate cd? *

What are other side effects people have besides Headache? *

Fatigue (feeling of tiredness): 8 people, 27.59%
Drug Ineffective: 7 people, 24.14%
Optic Atrophy (the loss of a proportion of optic disc nerve fibres): 6 people, 20.69%
Mydriasis (a dilation of the pupil): 5 people, 17.24%
Tardive Dyskinesia (a disorder that involves involuntary movements): 5 people, 17.24%
Nausea (feeling of having an urge to vomit): 4 people, 13.79%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 10.34%
Diarrhea: 3 people, 10.34%
Photophobia (extreme sensitivity to light): 3 people, 10.34%
Chills (felling of cold): 3 people, 10.34%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 20.69%
Abnormal Behavior: 3 people, 10.34%
Sinusitis (inflammation of sinus): 2 people, 6.90%
Autism (a mental condition, present from early childhood, characterized by difficulty in communicating and forming relationships with other people and in using language and abstract concepts): 2 people, 6.90%
Birth Control: 2 people, 6.90%
Body Height Below Normal: 2 people, 6.90%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.90%
Drowsiness: 2 people, 6.90%
Head Circumference Abnormal: 2 people, 6.90%
Hypersensitivity: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Metadate cd and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metadate cd:

Metadate cd (646 reports)

Headache treatments and more:

Headache (756,642 reports)

Browse all side effects of Metadate cd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Headache (3,747 drugs)

Browse all the conditions that are associated with Headache:

Headache (5,770 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Metadate cd) and Metadate cd (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.