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Metadate cd and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Metadate cd (methylphenidate hydrochloride), especially for people who are male, 10-19 old, have been taking the drug for 1 - 6 months also take Ritalin, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Insomnia when taking Metadate cd. It is created by eHealthMe based on reports of 514 people who have side effects when taking Metadate cd from the FDA, and is updated regularly.

What is Metadate cd?

Metadate cd has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 646 Metadate cd users. Check the latest studies of Metadate cd.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,119 drugs and 5,170 conditions by eHealthMe. Check the latest studies of Insomnia.

On Jul, 24, 2026

514 people reported to have side effects when taking Metadate cd.
Among them, 27 people (5.25%) have Insomnia.

Could Metadate cd cause Insomnia?

Among these 27 people:

How long have people been on Metadate cd when they have Insomnia? *

  • < 1 month: 27.27 %
  • 1 - 6 months: 45.45 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 27.27 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Insomnia when taking Metadate cd? *

  • female: 44.44 %
  • male: 55.56 %

What is the age of people who have Insomnia when taking Metadate cd? *

  • 0-1: 0.0 %
  • 2-9: 20 %
  • 10-19: 35 %
  • 20-29: 5 %
  • 30-39: 0.0 %
  • 40-49: 30 %
  • 50-59: 5 %
  • 60+: 5 %

What are other drugs people take besides Metadate cd? *

  1. Paxil: 4 people, 14.81%
  2. Ritalin: 4 people, 14.81%
  3. Xyrem: 3 people, 11.11%
  4. Ocrevus: 2 people, 7.41%
  5. Percocet: 2 people, 7.41%
  6. Effexor Xr: 2 people, 7.41%
  7. Concerta: 2 people, 7.41%
  8. Metformin: 2 people, 7.41%
  9. Ritalin La: 2 people, 7.41%
  10. Lyrica: 2 people, 7.41%

What are other side effects people have besides Insomnia? *

  1. Suicidal Ideation: 6 people, 22.22%
  2. Psychotic Disorder: 5 people, 18.52%
  3. Head Injury: 4 people, 14.81%
  4. Muscle Twitching: 4 people, 14.81%
  5. Energy Increased: 4 people, 14.81%
  6. Delusion (a false belief or opinion): 4 people, 14.81%
  7. Euphoric Mood (excessively happy but may become angry or irritable): 4 people, 14.81%
  8. Hallucinations (sensations that appear real but are created by your mind): 4 people, 14.81%
  9. Mania (a state of abnormally elevated or irritable mood): 4 people, 14.81%
  10. Drug Ineffective: 3 people, 11.11%

What are the existing conditions these people have? *

  1. Hypersensitivity: 4 people, 14.81%
  2. Birth Control: 3 people, 11.11%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 11.11%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 11.11%
  5. Sinusitis (inflammation of sinus): 2 people, 7.41%
  6. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 7.41%
  7. Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 2 people, 7.41%
  8. Muscle Spasms (muscle contraction): 2 people, 7.41%
  9. Disturbance In Attention: 2 people, 7.41%
  10. Stress And Anxiety: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Metadate cd and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metadate cd:

Insomnia treatments and more:

How severe was Insomnia and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metadate cd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Browse all the conditions that are associated with Insomnia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Metadate cd) and Metadate cd (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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