Methadone hydrochloride and Ocular hyperaemia - a phase IV clinical study of FDA data

Summary:

Ocular hyperaemia is reported as a side effect among people who take Methadone hydrochloride (methadone hydrochloride), especially for people who are male, 60+ old, also take Morphine Sulfate, and have Crohn's disease.

The phase IV clinical study analyzes which people have Ocular hyperaemia when taking Methadone hydrochloride. It is created by eHealthMe based on reports of 6,737 people who have side effects when taking Methadone hydrochloride from the FDA, and is updated regularly.

What is Methadone hydrochloride?

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. eHealthMe is studying from 8,598 Methadone hydrochloride users. Check the latest studies of Methadone hydrochloride.

What is Ocular hyperaemia?

Ocular hyperaemia (an abnormally large amount of blood in eye) is found to be associated with 1,357 drugs and 1,499 conditions by eHealthMe. Check the latest studies of Ocular hyperaemia.



On Jul, 09, 2026

6,737 people reported to have side effects when taking Methadone hydrochloride.
Among them, 16 people (0.24%) have Ocular hyperaemia.

Could Methadone hydrochloride cause Ocular hyperaemia?

Among these 16 people:

What is the gender of people who have Ocular hyperaemia when taking Methadone hydrochloride? *

  • female: 11.11 %
  • male: 88.89 %

What is the age of people who have Ocular hyperaemia when taking Methadone hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 25 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 25 %
  • 60+: 50 %

What are other drugs people take besides Methadone hydrochloride? *

  1. Prednisone: 7 people, 43.75%
  2. Morphine Sulfate: 7 people, 43.75%
  3. Lorazepam: 6 people, 37.50%
  4. Cipro: 6 people, 37.50%
  5. Morphine: 6 people, 37.50%
  6. Sucralfate: 5 people, 31.25%
  7. Inflectra: 5 people, 31.25%
  8. Acetaminophen And Codeine Phosphate: 4 people, 25.00%
  9. Clonazepam: 4 people, 25.00%
  10. Ondansetron: 3 people, 18.75%

What are other side effects people have besides Ocular hyperaemia? *

  1. Chills (felling of cold): 7 people, 43.75%
  2. Fever: 7 people, 43.75%
  3. Blood Urine Present: 6 people, 37.50%
  4. Dehydration (dryness resulting from the removal of water): 6 people, 37.50%
  5. Cystitis Interstitial (unknown cause characterized by bladder pain): 6 people, 37.50%
  6. Eye Discharge: 6 people, 37.50%
  7. Eye Swelling: 6 people, 37.50%
  8. Renal Disorder (kidney disease): 6 people, 37.50%
  9. Fatigue (feeling of tiredness): 6 people, 37.50%
  10. Groin Abscess (pus in groin): 6 people, 37.50%

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 37.50%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 25.00%
  3. Pneumonia: 2 people, 12.50%
  4. Non-Small Cell Lung Cancer Stage 0: 2 people, 12.50%
  5. High Blood Pressure: 2 people, 12.50%
  6. Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 6.25%
  7. Lung Cancer Metastatic (lung cancer spreads to other parts): 1 person, 6.25%
  8. Eye Infection: 1 person, 6.25%
  9. Back Pain: 1 person, 6.25%
  10. Asthma: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Methadone hydrochloride and have Ocular hyperaemia?

- Check whether Ocular hyperaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methadone hydrochloride:

Ocular hyperaemia treatments and more:

How severe was Ocular hyperaemia and when was it recovered:

Expand to all the drugs that have ingredients of methadone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methadone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ocular hyperaemia:

Browse all the conditions that are associated with Ocular hyperaemia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on methadone hydrochloride (the active ingredients of Methadone hydrochloride) and Methadone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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